Neurological Manifestations in Children Diagnosed With Inflammatory Bowel Disease

Neurological Manifestations in Children Diagnosed With Inflammatory Bowel Disease in Assiut University Child Hospital

screen for neurologic and psychiatric disorders in children and

adolescents with IBD.

Neurologic symptoms have a great importance in early diagnosis and

treatment preventing major morbidity and later sequelae, especially if they

precede GI symptoms

The prevalence of neurologic manifestations of IBD varies between 0.2% and

36%. Their pathogenesis of neurologic manifestations in IBD consists of 6

mechanisms: 1.malabsorption and nutritional deficiency 2.metabolic agents

3.infections complicating immune suppression 4.side effects of medications or

iatrogenic as a surgical complication 5.thromboembolism 6.immunological

factors

UC patients are similar to or higher than CD patients in the probability of

neurologic symptoms. Neurologic manifestations and complications include:

headache, dizziness, hypotonia, ADHD, tics, sensory complaints, seizures,

neuropsychiatric disorders, peripherial neuropathy, meningitis, vestibular

dysfunction, idiopathic IC hypertension, cerebral vasculitis, demyelinating

disorders and migraine

Inclusion Criteria:

• patients with IBD aged from from 1 to18 years old.

Exclusion Criteria:

• patients with IBD and aged above 18 years old or below 1 year old