screen for neurologic and psychiatric disorders in children and

adolescents with IBD.

Neurologic symptoms have a great importance in early diagnosis and

treatment preventing major morbidity and later sequelae, especially if they

precede GI symptoms

The prevalence of neurologic manifestations of IBD varies between 0.2% and

36%. Their pathogenesis of neurologic manifestations in IBD consists of 6

mechanisms: 1.malabsorption and nutritional deficiency 2.metabolic agents

3.infections complicating immune suppression 4.side effects of medications or

iatrogenic as a surgical complication 5.thromboembolism 6.immunological

factors

UC patients are similar to or higher than CD patients in the probability of

neurologic symptoms. Neurologic manifestations and complications include:

headache, dizziness, hypotonia, ADHD, tics, sensory complaints, seizures,

neuropsychiatric disorders, peripherial neuropathy, meningitis, vestibular

dysfunction, idiopathic IC hypertension, cerebral vasculitis, demyelinating

disorders and migraine

Inclusion Criteria:

• patients with IBD aged from from 1 to18 years old.

Exclusion Criteria:

• patients with IBD and aged above 18 years old or below 1 year old

Children diagnosed with inflammatory bowel disease in Assiut university child hospital