Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms

Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms: A Trial of tDCS and Cognitive Training 3-12 Months Post-mTBI

This project investigates an innovative combination of non-invasive neuromodulation (transcranial direct current stimulation - tDCS) and cognitive training as a novel treatment approach aimed at improving function in individuals suffering from persistent post-concussive syndrome (PPCS) following mild traumatic brain injury (mTBI).

Inclusion Criteria:

• Age 18-65
• Has sustained a single mTBI 3-12 months prior to enrollment
• Meets criteria for PPCS (assessed using the CP Screen)
• Has reliable access to a smartphone

Exclusion Criteria:

• Inability to provide informed consent or complete study procedures
• History of moderate/severe TBI
• Significant neurological or psychiatric disorders (other than PPCS-related symptoms like mild depression/anxiety)
• Substance dependence within the last six months
• Contraindications to tDCS (e.g., implanted metal, skin lesions on scalp)