PET-CT Imaging With PCD-CT

Advancing PET-CT Imaging With Photon Counting Detector CT

This pilot study evaluates the clinical utility of photon counting detector computed tomography (PCD-CT) in PET-CT imaging for head and neck cancer. Twenty adult patients undergoing standard-of-care PET-CT will also receive PCD-CT imaging. The study compares image quality and diagnostic confidence between conventional energy-integrating detector CT (EID-CT) and PCD-CT for attenuation correction and anatomical imaging.

Inclusion Criteria:

• Age ≥ 18 years
• Scheduled for or completed standard-of-care PET-CT of head and neck within ≤30 days

Exclusion Criteria:

• Non-diagnostic PET-CT
• Intervening therapy between scans
• Iodinated contrast allergy
• Renal insufficiency (GFR < 45)
• Pregnancy
• Gross motion artifacts