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This study was conducted to evaluate the potential role of using the cervical fascia flap over the pharyngeal closure line to enhance healing and subsequently to decrease the incidence of pharyngocutaneous fistula after total laryngectomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| cervical fascia flap group | Active Comparator |
| |
| conventional repair group | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Total laryngectomy | Procedure | pharyngeal repair after total larygectomy |
|
| Measure | Description | Time Frame |
|---|---|---|
| incidence of pharyngocutaneous fistula after total laryngectomy | Four weeks |
| Measure | Description | Time Frame |
|---|---|---|
| subjective assessment of the swallowing function after surgery | swallowing was evaluated subjectively by applying the Eating Assessment Tool (EAT-10) questionnaire | three months |
| objective assessment of the swallowing function after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine, Mansoura University | Al Mansurah | Dakahlia Governorate | 35511 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38940495 | Background | Zorlu ME, Kertmen C, Aysel A, Yilmaz F, Dalgic A, Muderris T. Use of Cervical Fascia to Prevent Pharyngocutaneus Fistula After Total Laryngectomy. Laryngoscope. 2024 Dec;134(12):4964-4970. doi: 10.1002/lary.31606. Epub 2024 Jun 28. | |
| 31712878 | Background | Wang M, Xun Y, Wang K, Lu L, Yu A, Guan B, Yu C. Risk factors of pharyngocutaneous fistula after total laryngectomy: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol. 2020 Feb;277(2):585-599. doi: 10.1007/s00405-019-05718-9. Epub 2019 Nov 11. |
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| ID | Term |
|---|---|
| D007822 | Laryngeal Neoplasms |
| ID | Term |
|---|---|
| D010039 | Otorhinolaryngologic Neoplasms |
| D006258 | Head and Neck Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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swallowing was evaluated objectively by functional endoscopic evaluation of swallowing (FEES)
| Three months |
| 33009930 | Background | Eid AM, Ebada HA, El-Fattah AMA, Tawfik A. Platelet-rich fibrin: an autologous biomaterial for healing assistance of pharyngeal repair in total laryngectomy. Eur Arch Otorhinolaryngol. 2021 Feb;278(2):463-470. doi: 10.1007/s00405-020-06404-x. Epub 2020 Oct 3. |
| 32836041 | Background | Park J, Chang C, Kwon D. Use of fibrin adhesive for preventing pharyngocutaneous fistula in total laryngectomy. Am J Otolaryngol. 2020 Nov-Dec;41(6):102674. doi: 10.1016/j.amjoto.2020.102674. Epub 2020 Aug 13. |
| D007818 |
| Laryngeal Diseases |
| D012140 | Respiratory Tract Diseases |
| D012142 | Respiratory Tract Neoplasms |
| D010038 | Otorhinolaryngologic Diseases |