Neurological Events and Unforeseen Risks After Locoregional-anesthesia

Neurological Events and Unforeseen Risks After Locoregional-anesthesia

This is a multicenter, prospective, observational study aimed at determining the incidence of neurological and non-neurological complications following locoregional anesthesia procedures. The study will collect data on events such as nerve injury, hematoma, pneumothorax, and local anesthetic systemic toxicity.

Locoregional anesthesia is generally considered safe, but rare neurological and systemic complications have been reported. Current data on the true incidence of these complications are limited and often derived from small sample sizes or registries. The NEURAL study aims to fill this knowledge gap by prospectively collecting data on complications following single-shot nerve blocks in the upper limb, lower limb, and fascial plane. In addition to incidence, the study will investigate potential risk factors for these complications.

Inclusion Criteria:

• Age ≥ 18 years.
• Scheduled to undergo a single-shot nerve or fascial plane block.
• Ability to provide written informed consent.

Exclusion Criteria:

• Performance of more than one single-shot nerve or fascial plane block within the same anatomical region or sensory distribution during the same procedure.
• Use of continuous nerve or fascial plane catheter-based anesthesia.
• Presence of a language barrier that, in the investigator's judgment, would prevent adequate follow-up.