Revascularization with triple antibiotic paste as intracanal medication

Revascularization with grape seed extract as intra canal medication

Revascularization with glycyrrhizin as intracanal medication

Grape seed extract in form of hydrogel with concentration 6.5 % left in canal for one week

Microbiological evaluation The number of E. faecalis will be digitally counted.

Clincal success will be assessed using following criteria of success according to clinical scoring system

Absence of :

• Pain,

• Soft tissue swelling

• soft tissue inflammation

• Sinus tract

• tenderness to percussion

• tooth mobility. Clinical score Clinical symptom Definition

  1. asymptomatic Pathology: absent Normal functioning Mobility (physiological) ≤1mm
  2. Slight discomfort, short-lived Pathology: questionable Percussion sensitivity Gingival inflammation (due to poor oral hygiene) Mobility (physiological) > 1mm, but <2mm
  3. Minor discomfort, short-lived Pathology: initial changes present Gingival swelling (not due to poor oral hygiene) Mobility > 2mm, but < 3 mm
  4. Major discomfort, long-lived extract immediately Pathology: late changes present Spontaneous pain Gingival swelling (not due to poor oral hygiene) Periodontal pocket formation(exudate) Sinus tract present Mobility ≥ 3mm Premature tooth loss, due to pathology

After tweleve months take periapical radiograph to detection normal lamina dura and increase in root thikness and length. Criteria for success according to radiographic scoring system