The goal of the study is to check efficacy of probiotics in preventing necrotizing enterocolitis. The main questions would be if the preterm baby developed NEC or not.

: In the last five years, many systematic reviews have shown the benefit of Probiotics in prevention of NEC and Sepsis in preterm babies but most of these studies have been done in the developed countries. Although the overall benefit has been tilted In favor of use of probiotic however a definitive consensus has not been reached due to inconsistencies in results. Moreover, the impact of multistrain probiotics in our particular population has not been studied, which provides the rationale for our research

Inclusion Criteria:

• Male and female preterm infants with a gestational age less than 35 weeks.
• All indoor patients and outdoor patients who present within 24hrs of birth

Exclusion Criteria:

• • Infants with congenital or developmental gastrointestinal disorders for example omphalocele, malrotation, gastroschisis.

  • Infants with severe sepsis or gastrointestinal bleeding on presentation