Optimised Osmolality in Oral Supplements Optimised Osmolality in Oral Supplements

Goldilocks' Zone: Optimised Osmolality in Supplements for the Patient With an Ileostomy

Quasi-randomized, crossover intervention study, testing osmolality in oral drinks and effect on 6-hours ileostomy output in adult patients with an ileostomy

14 patients with ileostomies were included in a quasi-randomized, crossover intervention study. Each patient ingested between 3-18 different supplements during separate 6-hours intervention periods. Ileostomy output and urine volume will be collected. Outcome measures include faecal wet-weight, urine volume, electrolytes, osmolality, and body composition measured with bioelectrical impedance analysis.

Inclusion Criteria:

1. age 18 years or higher
2. ileostomy formed at least 8 weeks before enrolment
3. consent to participate

Exclusion Criteria:

1. pregnancy
2. known chronic kidney disease
3. known diabetes mellitus
4. too long driving distance
5. parenteral nutrition/fluid more than 6 litres per month