The Impact of Stationary Combined Exercise on Adiponectin and Hs-CRP Levels in Overweight Women

The Impact of Stationary Combined Exercise on Adiponectin and High-Sensitivity C-Reactive Protein Levels in Overweight Women

This study looked at whether a specific exercise program can improve inflammatory markers in overweight young women. We tested an eight-week, circuit-style exercise program that combines aerobic and resistance activities (e.g., sit-ups, step jumps, push-ups, jump rope, jumping jacks, medicine-ball lifts). Participants exercised four times per week at a moderate-to-high intensity, with a warm-up and cool-down at each session.

Twenty-two women (ages 20-30 years; BMI 25-31 kg/m²) were randomly assigned to one of two groups: (1) the exercise group completed the training program; (2) the control group continued usual daily activities without a structured program. Before starting and 48 hours after finishing the program, we took fasting blood samples to measure two markers: adiponectin (a hormone made by fat tissue that supports healthy metabolism and has anti-inflammatory effects) and high-sensitivity C-reactive protein (hs-CRP) (a blood marker of inflammation and cardiovascular risk).

The main outcomes were the changes in adiponectin and hs-CRP from before to after the 8-week period. We also recorded weight, body mass index (BMI), body fat percentage, and fitness (VO₂max). The study was conducted at the Exercise Physiology Laboratory, College of Physical Education and Health, Chongqing College of International Business and Economics (Chongqing, China). The research ethics committee approved the protocol, and all participants provided written informed consent.

Recruitment and data collection are complete. Findings suggest that this circuit-based exercise program can increase adiponectin and lower hs-CRP, alongside improvements in body composition, in overweight young women.

Inclusion Criteria:

Female sex Age 20 to 30 years BMI 25 to 31 kg/m² Body weight 63 to 87 kg Generally healthy, without diagnosed chronic illness Willing and able to provide written informed consent Willing to refrain from vigorous physical activity for 48 hours before blood sampling Able to attend 4 supervised training sessions per week for 8 weeks (if assigned to intervention)

Exclusion Criteria:

History of cardiovascular disease, hypertension, or diabetes Current smoking or tobacco use Current use of medications or supplements that affect metabolism or inflammatory markers Pregnancy or breastfeeding Contraindications to moderate-to-high intensity exercise on screening Participation in regular vigorous exercise training within the past 6 months Inability or unwillingness to comply with study procedures (e.g., missing >2 consecutive training sessions)