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The purpose of this study is to assess the effect of food on the drug levels of Admilparant
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Part 1: Treatment A | Experimental |
| |
| Part 1: Treatment B | Experimental |
| |
| Part 2: Treatment C | Experimental |
| |
| Part 2: Treatment D | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Admilparant | Drug | Specified dose on specified days |
|
| Measure | Description | Time Frame |
|---|---|---|
| Maximum observed plasma concentration (Cmax) | Up to 13 days | |
| Area under the concentration-time curve from time zero to time of last quantifiable concentration (AUC(0-T)) | Up to 13 days | |
| Area under the concentration-time curve from time zero extrapolated to infinite time (AUC(INF)) | Up to 13 days |
| Measure | Description | Time Frame |
|---|---|---|
| Time of maximum observed plasma concentration (Tmax) | Up to 13 days | |
| Terminal half-life (T-HALF) | Up to 13 days | |
| Apparent total body clearance (CLT/F) |
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Inclusion Criteria
Exclusion Criteria
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| Name | Affiliation | Role |
|---|---|---|
| Bristol-Myers Squibb | Bristol-Myers Squibb | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Local Institution - 0002 | Lenexa | Kansas | 66219-9746 | United States | ||
| Local Institution - 0001 |
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| Label | URL |
|---|---|
| BMS Clinical Trial Information | View source |
| BMS Clinical Trial Patient Recruiting | View source |
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BMS will provide access to individual anonymized participant data upon request from qualified researchers, and subject to certain criteria. Additional information regarding Bristol Myer Squibb's data sharing policy and process can be found at: https://www.bms.com/researchers-and-partners/clinical-trials-and-research/disclosure-commitment.html
See plan description
See plan description
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| Up to 13 days |
| Apparent volume of distribution (Vz/F) | Up to 13 days |
| Number of participants with adverse events (AEs) | Up to 13 days |
| Number of participants with a change in clinical laboratory values | Up to 13 days |
| Number of participants with a change in vital sign measurements | Up to 13 days |
| Number of participants with a change in physical examination results | Up to 13 days |
| Number of participants with a change in 12-lead electrocardiogram (ECG) results | Up to 13 days |
| Salt Lake City |
| Utah |
| 84124-1365 |
| United States |