The purpose of this study is to improve ways of providing mental health support to Spanish-speaking Latino participants who have cancer and experience depression, insomnia, and fatigue. Investigators will test a special mental health intervention called DESCANSO/REST (Depresión/Depressed Mood, Cansancio/Fatigue, and Sueño/Sleep). The intervention can be delivered through telehealth.

Provider Eligibility Criteria:

Participant eligibility will be determined by a self-report screener. Inclusion Criteria Self-Report Criteria

• Mental health provider
• Treats Latino cancer patients and/or survivors
• Has at least 3 years of clinical experience providing psychosocial services to cancer patients and/or survivors
• Able to read Spanish determined by the question: "Can you read in Spanish? Yes/No"

Patient Eligibility Criteria:

A patient cannot be considered eligible for this study unless ALL of the following conditions are met. Participant eligibility will be determined by an initial EMR review followed by a self-report screener.

Inclusion Criteria EMR Criteria

• Documentation of Disease

  o Pathologically confirmed solid tumor cancer (either most recent or new diagnosis)

• Definition of Disease [or Measurable Disease]

  o Diagnosed with stages I, II, or III

• Prior Treatment

  • Currently undergoing systemic therapy (chemotherapy, radiation therapy, and/or immunotherapy) or within the first year following completion of systemic therapy Self-Report Criteria
  • Age ≥ 21 years
  • Lives in mainland U.S. or Puerto Rico
  • Identifies as Latino/a or Hispanic
  • Reports Spanish as their preferred language
  • Speaks Spanish "Very well" or "Well" as determined by the question: "How well do you speak Spanish?"
  • Presence of fatigue and disturbed sleep determined by a score of ≥ 3 on the MD Anderson Symptom Inventory

Exclusion Criteria EMR Criteria

o In the judgment of the treating physician, protocol investigators, and/or study staff, presence of cognitive impairment (e.g., delirium or dementia) sufficient to preclude meaningful informed consent and/or study participation

Self-Report Criteria

• History of comorbidities within the last 12 months associated with fatigue and poor sleep, including hypothyroidism or abnormal thyroid function, sleep apnea, chronic obstructive pulmonary disease, neuromuscular disease, alcohol or drug abuse
• Pregnant or lactating, women only
• Presence of suicidal risk determined by any affirmative response on the Columbia-Suicide Severity Rating Scale

• Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.