Cannabis Reduction and Functional Outcomes

Prospective Changes in Patient-reported and Objective Functioning Following Reduction of Cannabis Use

This study evaluates the effects of cannabis use reduction among adults diagnosed with cannabis use disorder (CUD). Participants will undergo an 8-week intervention combining motivational interviewing, computerized cognitive behavioral therapy (CBT4CBT), and financial incentives for reduction in urinary cannabinoids. The study aims to assess improvements in cannabis-related problems, sleep, cognitive performance, CUD severity, and quality of life.

Inclusion Criteria:

• Age 18+
• Urinary cannabinoid level ≥ 50 ng/mL
• DSM-5 diagnosis of CUD (mild, moderate, or severe)
• Willingness to attempt cannabis reduction
• Completion of Intake Visit

Exclusion Criteria:

• Serious medical/psychiatric conditions
• Pregnancy or breastfeeding
• Use of cannabis in past 30 days was for medical purposes only
• Discontinuation or reduction of cannabis use may exacerbate a pre-existing condition
• Cognitive or understanding difficulties, as evidenced by inability to pass informed consent quiz