Photoacoustic Imaging of Foot Wound

Photoacoustic Imaging in Wound Evaluation and Treatment Guidance

This pilot device trial aims to test the feasibility of using photoacoustic images to monitor tissue perfusion and to guide post-surgical wound treatment. Through this pilot study, the investigators will test the feasibility, identify any practical issues, and acquire essential information (e.g., drop-off rate, variation in wound healing rate) to guide future large-scale studies.

This pilot device trial aims to test the feasibility of using photoacoustic images to monitor tissue perfusion and to guide post-surgical wound treatment. Through this pilot study, the investigators will test the feasibility, identify any practical issues, and acquire essential information (e.g., drop-off rate, variation in wound healing rate) to guide future large scale studies.

For recruited patients, wound care will be guided by both photoacoustic imaging and Kent imaging, a multi-spectral imaging technique for tissue oxygenation mapping. None of the techniques is currently used in the clinic as standard care.

Inclusion Criteria:

• Patients with a chronic wound on the foot that is presumed to be due to arterial insufficiency.

Exclusion Criteria:

• Patients with a massive deep tissue infection.
• Patients with preexisting skin conditions, such as melanoma, psoriasis, in areas close to the wound(s).
• Noncompliant patients who do not adhere to care plans.
• Pregnant women.
• Adults unable to consent.