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| ID | Type | Description | Link |
|---|---|---|---|
| A534300 | Other Identifier | UW Madison | |
| Protocol Version 3/21/25 | Other Identifier | UW Madison |
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The purpose of this study is to determine the potential influence of intraoperative dermabrasion on scars following Mohs Micrographic Surgery (MMS). Researchers are trying to determine if dermabrasion, a method to gently remove the top layer of your skin, is a good or bad tool to improve scar appearance after healing. The use of dermabrasion technique in this study is considered investigational. 50 participants will be enrolled and on study for up to 6 months.
Primary Objective: Scar assessment at 3 months postoperatively by utilizing observer component of Patient and Observer Scar Assessment Scale (POSAS)
Secondary Objectives:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A: Superior Side of the Wound | Experimental | The participant's wound will be labeled A if it is on the left or superior side of the investigator |
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| B: Inferior Side of the Wound | Experimental | The participant's wound will be labeled B if it is on the right or inferior side of the investigator |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dermabrasion | Procedure | First, both sides of the wound will be sutured together with a subcutaneous (bottom) layer of stitches. Next, a predetermined, concealed randomization number will be obtained which will specify which side, A or B, will be treated with dermabrasion. An electrocautery scratch pad will be used along the wound edge of the intervention side until pin-point bleeding is achieved. This will add no additional time to the standard of care surgery time. The wound will then be closed with an epidermal (top) layer of stitches, as is the standard of care. |
| Measure | Description | Time Frame |
|---|---|---|
| POSAS Observer Score at 3 months post-surgery | The investigators hypothesize that the side of the wound treated with intraoperative dermabrasion will have superior cosmesis as evaluated by the observer components of POSAS when evaluated at 3 months postoperatively. Two blinded reviewers will provide the POSAS Observer score which evaluates scar vascularity, pigmentation, thickness, relief, pliability, and surface area, each from 1 to 10 where higher scores indicate worse scars. Total scores are summed and range from 6-60. | 3 months post-surgery |
| Measure | Description | Time Frame |
|---|---|---|
| POSAS Patient Score at 3 months post-surgery | The investigators hypothesize that the side of the wound treated with intraoperative dermabrasion will have superior cosmesis as evaluated by the patient components of POSAS when evaluated at 3 months postoperatively. The POSAS Patient score evaluates scar pain, itching, color, stiffness, thickness, and irregularity, each from 1 to 10 where higher scores indicate worse symptoms or physical scar characteristics. Total scores are summed and range from 6-60. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Gloria Xu, MD, PhD | UW School of Medicine and Public Health | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UW Health Mohs Surgery Clinic | Madison | Wisconsin | 53717 | United States |
Study data shared publicly (i.e.: publications, conference presentations, etc.) will be deidentified, photographs shared publicly will have participant's eyes and other identifiable features blocked to protect identity.
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| ID | Term |
|---|---|
| D002921 | Cicatrix |
| ID | Term |
|---|---|
| D005355 | Fibrosis |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D003869 | Dermabrasion |
| ID | Term |
|---|---|
| D003357 | Cosmetic Techniques |
| D013812 | Therapeutics |
| D062109 | Dermatologic Surgical Procedures |
| D019651 | Plastic Surgery Procedures |
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This is a single center, randomized, evaluator and participant blind, split wound study.
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| 3 months post-surgery |
| POSAS Overall Patient Opinion Score at 3 months post-surgery | The investigators hypothesize that the side of the wound treated with intraoperative dermabrasion will have superior cosmesis as evaluated by the patient components of POSAS when evaluated at 3 months postoperatively. The POSAS overall patient opinion score ranges from 1 to 10 where higher scores indicate worse symptoms or physical scar characteristics. | 3 months post-surgery |
| Number of Complications | 3 months post-surgery |
| D013514 | Surgical Procedures, Operative |