Antithrombotic Strategies in Coronary Artery Dilatations and Aneurysms

Antithrombotic Strategies in Coronary Artery Dilatations and Aneurysms

Objectives: The discovery of aneurysmal or ectatic lesions of the coronary arteries during coronary angiography or coronary CT angiography poses a triple challenge in terms of aetiology, treatment and prognosis. The aim of this study, based on coronary angiograms performed over a 10-year period at the Centre Hospitalier de Versailles, was to determine which antithrombotic treatment was routinely prescribed to patients with ACC or AEC, the evolution of this long-term treatment, and to analyse the association between the presence/absence of anticoagulant treatment and the rates of ischaemic cardiovascular events and haemorrhagic complications.

Materials and methods: This is a non-interventional, observational, single-centre study conducted at the Versailles Hospital Centre from 2013 to 2023, based on the department's coronary angiography registry. The study included adult patients, living or deceased, hospitalised in the cardiology department who underwent coronary angiography between 1 January 2013 and 31 December 2023, which showed the presence of aneurysms or ectatic atheroma with bi- or tri-vessel coronary involvement.

Inclusion Criteria:

• Patient > 18 years old
• Patient living or deceased
• Patient with aneurysmal or ectatic coronary artery disease with bi- or tri-truncular involvement at coronary angiography.

Exclusion Criteria:

• Patient < 18 years old
• Monotruncal aneurysmal or ectatic disease
• Absence of coronary aneurysm / ectasia
• Patient's opposition to participation in research