Predicting Factors of Post-Total Thyroidectomy Hypocaӏcemia | NCT07211581

Studies
Predicting Factors of Post-Total Thyroidectomy Hypocaӏcemia

NCT07211581

Sponsor

Al Safwa University College

Status

Completed

Last Update Posted

Oct 8, 2025Actual

Enrollment

123Actual

Phase

Not provided

Conditions

Hypocalcemia After Total Thyroidectomy

Interventions

total thyroidectomy

Countries

Tunisia

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Sep 2025

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Sep 17, 2025Actual

Primary Completion Date

Sep 17, 2025Actual

Completion Date

Sep 17, 2025Actual

First Submitted Date

Sep 17, 2025

First Submission Date that Met QC Criteria

Sep 30, 2025

First Posted Date

Oct 8, 2025Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Sep 30, 2025

Last Update Posted Date

Oct 8, 2025Actual

Sponsor/Collaborators Module

Responsible Party, by Official Title

Mohammed AbdulZahra Sasaa, Predicting Factors of Post-Total Thyroidectomy Hypocaӏcemia, Al Safwa University CollegePrincipal Investigator

Lead Sponsor

Al Safwa University CollegeOTHER

Collaborators

Not provided

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

Predicting post-total thyroidectomy hypocalcemia involves a combination of patient-specific, disease-related, and surgical factors. Key predictive factors include the intrinsic characteristics of the thyroid disease, pre-operative levels of calcium and vitamin D, the degree of parathyroid gland manipulation or injury, advanced age, and pre-existing hyperthyroidism. While no single factor is definitive, a low post-operative parathyroid hormone (iPTH) level is a strong indicator of developing hypocalcemia

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

123Actual

Arms/Interventions Module

Arm Groups

Not provided

Interventions

Name	Type	Description	Arm Group Labels	Other Names
total thyroidectomy	Procedure	both lobes removed and observe the calcemic level

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
hypocalcemia incidence		1 day and 2 weeks after surgery
hypocalcemia other factors related to clinical status.	Comparison of Serum Calcium levels of the studied group reported Comparison of PTH levels between hypocaӏcemia and Eucalcemic	1 day and 2 weeks after surgery

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

patients requiring total thyroidectomy.
age between 18-75 years old
both gender
no co-existing disease.

Exclusion Criteria:

1. previous hemithyroidectomy, lobectomy, resection of the parathyroid gland. 2. 2. patients with missing laboratory data, previous subtotal thyroidectomy.

3. diagnosed pathology of the parathyroid gland

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

21 Years

Maximum Age

76 Years

Standard Ages

AdultOlder Adult

Study Population

A total of 123 patients who underwent total thyroidectomy for various thyroid diseases were included in the study, performed by a group of surgeons.

Sampling Method

Probability Sample

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
1. Ali Fadhil Zaidan, PhD	mustaqbal university	Study Chair

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Mustaqbal University		Sfax	Safx	54001	Tunisia

IPD Sharing Statement Module

Plan to Share IPD

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided

Condition Browse Module

MeSH Terms

ID	Term
D006996	Hypocalcemia

Ancestor Terms

ID	Term
D002128	Calcium Metabolism Disorders
D008659	Metabolic Diseases
D009750	Nutritional and Metabolic Diseases
D014883	Water-Electrolyte Imbalance

Browse Leaves

Not provided

Browse Branches

Not provided