Scalp Acupuncture Combined With rTMS for Upper Limb Motor Dysfunction in Stroke: A Brain Network Study

Research Protocol for a Randomized Controlled Trial on Brain Network Study of Upper Limb Motor Dysfunction in Stroke Patients Treated With Scalp Acupuncture Combined With rTMS

This study aims to compare the improvement effects of the rTMS (repetitive transcranial magnetic stimulation) combined with conventional rehabilitation therapy group with the rTMS combined with scalp acupuncture and conventional rehabilitation therapy group. Through statistical analysis of the results obtained from functional near-infrared spectroscopy technology during task states, the investigators elucidate the neuroregulatory mechanism of scalp acupuncture combined with rTMS in improving upper limb motor function in stroke patients under MEP localization, and provide evidence for a more optimal rehabilitation program for post-stroke upper limb motor dysfunction.

Inclusion Criteria:

• Meet the diagnostic criteria for stroke (symptoms and signs, imaging indicators, etc.), and are independently diagnosed by two deputy chief physicians
• Age 18-70 years old, first episode, duration 1-6 months
• The diagnostic criteria for upper limb dysfunction align with the Brunnstrom staging system: patients in Brunnstrom stages II to IV. Stage II: patients exhibit associative responses and can perform coordinated movements, with minimal voluntary movements; Stage III: patients show voluntary coordinated movements, such as grasping with the hand but not extending; Stage IV: patients can perform isolated movements, such as pinching with the hand and limited extension
• No severe visual or hearing impairment, able to cooperate with relevant assessments and tests
• The score of the Mini-Mental State Examination is ≥20 points
• Vital signs are stable, with no signs of progressive neurological symptoms
• The patient or legal guardian agrees and signs the informed consent form

Exclusion Criteria:

• Severe visual impairment, hemispatial neglect, body image disorder
• Individuals who cannot undergo rTMS treatment due to reasons such as metal implants, cardiac pacemakers, or skull defects
• Previous history of brain tumor, brain trauma, epilepsy, and risk of epileptic seizures
• Any other factors that affect assessment and treatment
• Dysfunction of limb movement caused by other reasons (such as trauma, etc.)