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The goal of this split-mouth randomized controlled trial is to assess whether the timing of extraction space closure-early vs. delayed initiation-affects the incidence of gingival cleft development in orthodontic patients. The main question it aims to answer is:
Does the incidence of gingival cleft development get influenced by the specific time point at which orthodontic space closure is initiated following extraction?
Quadrants will be assigned to the early movement group and the other to the delayed movement group and extractions will be performed accordingly. These will be assessed for the effect on development of gingival cleft development.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Early movement group | Experimental | Canine retraction will be started 1 week after extraction |
|
| Delayed Movement | Experimental | Canine retraction will be started 8 weeks after extraction |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Early space closure | Other | Space closure will be started 1 week after extraction |
| |
| Measure | Description | Time Frame |
|---|---|---|
| presence of gingival clefts after space closure initiation | The primary outcome will be the presence of gingival clefts, which will be measured at 3 months and 6 months after space closure initiation | start of canine retraction to its completion (approximately 6 months) |
| Measure | Description | Time Frame |
|---|---|---|
| craniofacial growth pattern | craniofacial growth pattern from sum of posterior angles | craniofacial growth pattern will be measured at baseline |
| gingival biotype | gingival biotype by measuring thickness of gingiva using spreader of size 15 |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bahria University of Health Sciences Karachi | Recruiting | Karachi | Sindh | Pakistan |
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| ID | Term |
|---|---|
| D005882 | Gingival Diseases |
| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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split-mouth randomized controlled study
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| Delayed space closure |
| Other |
Space closure will be started 8 weeks after extraction |
|
| At baseline (immediately prior to tooth extraction) |
| buccal bone dehiscence | bone dehiscence will be measured utilizing the periodontal probe(in mm) from the distal marginal ridge of premolar as reference point, on both the buccal and palatal/lingual side. | Immediately post extraction |
| canine bulbosity | Maximum height of contour of canine will be measured on the pretreatment cast using the digital vernier caliper | will be measured at baseline |