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Evaluate the safety and efficacy of postoperative Pre-emptive EVT (PEVT) in reducing the incidence of anastomotic leaks within 30 days after surgery in patients with colorectal cancer. Compare the differences between the PEVT group and the control group in terms of operation time, length of hospital stay, and total medical costs. Analyze the incidence of other postoperative complications in the two groups, such as wound infection, abdominal abscess, and intestinal obstruction. Assess the impact of PEVT on postoperative recovery indicators, including time to first flatus, time to first defecation, and time to ambulation. Observe the occurrence of PEVT-related adverse events, such as device displacement, bleeding, and infection.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pre-emptive Endoscopic Vacuum Therapy | Experimental | After the anastomosis is completed and confirmed by endoscopy to be intact and free of bleeding, immediately perform Pre-emptive Endoscopic Vacuum Therapy(PEVT). |
|
| No Pre-emptive Endoscopic Vacuum Therapy | No Intervention | After the anastomosis, only routine colonoscopy was performed without PEVT device, and other steps were consistent with the PEVT group. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PEVT | Device | PEVT Procedures After the anastomosis is completed and endoscopy confirms that the anastomotic site is intact and without bleeding, the following procedures are carried out immediately (usually within 30 minutes after the completion of the anastomosis):
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of Participants with Anastomotic Leak within 30 days | Count the number of participants who develop anastomotic leak within 30 days after colorectal cancer surgery. | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Number of Participants with Postoperative Complications within 30 days | Count the number of participants who develop postoperative bleeding, anastomotic stenosis, and intra-abdominal infection within 30 days after colorectal cancer surgery. | 30 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yunhong Tian Tian, doctor | Contact | +8613508087719 | drtianyunhong@126.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nanchong Central Hospital | Recruiting | Nanchong | Sichuan | 637000 | China |
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|
| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| D057868 | Anastomotic Leak |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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