AI-Guided Left Bundle Branch Area Pacing

A Pilot Study Assessing Outcomes Of Artificial Intelligence-Guided Left Bundle Branch Area Pacing For Cardiac Resynchronization In Heart Failure

The purpose of this study is to compare the effectiveness of AI-guided LBBAP versus conventional LBBAP (not AI-guided) in improving CRT response rates and clinical outcomes.

Inclusion Criteria

• Age: 18 years or older.
• Left Ventricular Ejection Fraction (LVEF): <50% within 6 months prior to enrollment.
• QRS Duration: Resting QRS duration ≥ 130 ms on ECG OR anticipated right ventricular pacing > 40% OR device in place with right ventricular pacing > 40% within 6 months prior to enrollment.
• Medical Therapy: Optimized on guideline-directed medical therapy for heart failure.
• AI-ECG probability of low LVEF: >0.5

Exclusion Criteria

• Age less than 18 years old
• Inability to follow-up
• Pregnancy