The objective of this Pilot Study is to demonstrate the efficacy of the Hemocept device in detecting changes in arterial blood volume and cardiac efficiency.

Inclusion Criteria:

• Subjects or representatives must have voluntarily signed the informed consent form before any study related procedures.

• Subjects can be any gender but must be between (and including) the ages of 18 and 80.

• Subject ls being treated by the participating healthcare facility .

  ., Subject requires a trans-aortic valve replacement.

• Subject is able and willing to provide informed consent and HIPM authorization.

• Subject is able and willing to meet all study requirements.

Exclusion Criteria:

• Subject is pregnant, breast-feeding, or intends to become pregnant during the course of the study.

• Subject has a personal medical history that includes:

  • Long O-T syndrome
  • Cardiac channelopathies
  • Seizures

Subjects will be between 18 and 80 and above who meet all the Inclusion/Exclusion criteria

There is not a plan to make IPD available