Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine

Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine

This project aims to investigate the impact of e-cigarette flavors and usage patterns on achieving harm-reduction milestones in a sample of cigarette smokers with opioid use disorder who are taking buprenorphine

Inclusion Criteria

• Age ≥21 years
• Smoke ≥5 CPD for ≥1 year
• Daily CC smoker
• Willing to switch to EC
• Exhaled CO ≥6 ppm
• Diagnosed with OUD
• Stable on bupropion treatment
• In good physical and mental health
• Able to use a smartphone
• Willing to participate in all study components
• Able to provide informed consent Exclusion Criteria
• Interested in quitting CC (contemplation stage of change)
• Use of EC on ≥4 of the past 30 days
• Use of other tobacco products (e.g., cigars, smokeless tobacco) on ≥9 days of the past 30 days
• Use of nicotine replacement therapy, smoking cessation medication, or a cessation attempt in the past 30 days
• Hypertension
• Medical condition that would contraindicate participation
• Meet DSM-V criteria for major depressive episode, psychotic episode, or manic episode
• Current suicidal ideation or suicide attempt in the past year
• Psychiatric hospitalization in the past year
• Contemplating pregnancy, currently pregnant, or breastfeeding
• Unable to speak and/or read English