Bond Strength Evaluation | NCT07196618

Studies
Bond Strength Evaluation

NCT07196618

Sponsor

Al-Azhar University

Status

Active, not recruiting

Last Update Posted

Dec 18, 2025Actual

Enrollment

30Estimated

Phase

Not Applicable

Conditions

Bonding

Interventions

dimethyl sulfoxide
Cholorhexidine

Countries

Egypt

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Sep 2025

Overall Recruitment Status or Expanded Access Status

Active, not recruiting

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Sep 1, 2025Actual

Primary Completion Date

Feb 2026Estimated

Completion Date

Mar 2026Estimated

First Submitted Date

Aug 9, 2025

First Submission Date that Met QC Criteria

Sep 26, 2025

First Posted Date

Sep 29, 2025Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Dec 10, 2025

Last Update Posted Date

Dec 18, 2025Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Yes

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Yes

FDAAA801 Violation

Not provided

Description Module

Brief Summary

This study was evaluated the effect of dimethyl sulfoxide pretreatment on tensile bond strength and nanoleakage of resin composite bonded to aged dentin.

Detailed Description

Not provided

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not Applicable

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

30Estimated

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
DMSO	Active Comparator		Drug: dimethyl sulfoxide
CHX	Active Comparator		Drug: Cholorhexidine

Interventions

Name	Type	Description	Arm Group Labels	Other Names
dimethyl sulfoxide	Drug	dentin pretreated using dimethyl sulfoxide and follow up of patients at 2 weeks, 3 months and 6 months	DMSO

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
clinical assessment evaluation using the FDI world dental federation criteria		post operative 2 weeks

Secondary Outcomes

Measure	Description	Time Frame
clinical assessment evaluation using the FDI world dental federation criteria		post operative 3 months and 6 months

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Patients included in the study will be required to present at least one of non caries cervical lesion with sclerotic dentin without pulpal involvement.
Age of patient: 50 - 75 years
Patients with non caries cervical lesion will be standardized by clinical performance (FDI world dental federation).

Exclusion Criteria:

Teeth with deep dentinal lesions with pulpal involvement, abscess, pain or swelling
Developmental disorders and adjacent soft tissue lesions
Patients with systemic illness will be excluded.

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

50 Years

Maximum Age

75 Years

Standard Ages

AdultOlder Adult

Study Population

Not provided

Sampling Method

Not provided

Name	Affiliation	Role
Aisha Zahran	Al-Azhar University	Study Director

IPD Sharing Statement Module

Plan to Share IPD

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided

Intervention Browse Module

MeSH Terms

ID	Term
D004121	Dimethyl Sulfoxide

Ancestor Terms

ID	Term
D013454	Sulfoxides
D013457	Sulfur Compounds
D009930	Organic Chemicals

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Browse Branches

Not provided