Clinical and Biological Signs of Dapagliflozin Overdose in ICU Patients With Metformin Poisoning

Clinical and Biological Signs of Dapagliflozin Overdose in ICU Patients With Metformin Poisoning

This study looks at patients admitted to intensive care for drug poisoning involving metformin, a common diabetes medication. Researchers will compare two groups: patients who overdosed on metformin alone and those who took both metformin and dapagliflozin, another diabetes drug. The goal is to find clinical or laboratory signs that could help doctors quickly recognize a dapagliflozin overdose in this context, which could improve treatment and patient outcomes.

Inclusion Criteria:

• Adults aged 18 years or older
• Admission to an intensive care unit (ICU) due to acute drug poisoning
• Documented exposure to either:
• Metformin alone
• Metformin in combination with dapagliflozin

Exclusion Criteria:

• Patients under 18 years of age
• No exposure to metformin
• Exposure to dapagliflozin without metformin