Ginger to Prevent Nausea and Vomiting After Laparoscopic Cholecystectomy

Preoperative Ginger for the Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy: A Double-Blind Randomized Controlled Trial

This study aims to evaluate whether preoperative oral administration of ginger (800 mg, given 2 hours before surgery) reduces the incidence and severity of postoperative nausea and vomiting (PONV) within the first 24 hours after laparoscopic cholecystectomy.

Inclusion Criteria:

• Age ≥ 18 years.
• Scheduled for elective laparoscopic cholecystectomy under general anesthesia.
• American Society of Anesthesiologists (ASA) physical status I-III.
• Able to understand the study procedures and provide written informed consent.

Exclusion Criteria:

• Known allergy or hypersensitivity to ginger
• Documented history of bleeding disorders or current treatment with anticoagulant agents
• History of severe postoperative nausea and vomiting or an Apfel score of 4
• Administration of antiemetic drugs or corticosteroids during the preoperative period
• Pregnancy or breastfeeding
• Active gastrointestinal or liver disease