Home-based Under Mattress Monitor for OSA

Home-Based Under-Mattress Monitoring Device to Estimate Mandibular Advancement in Oral Appliance Therapy for Obstructive Sleep Apnea

The aim of the study is to evaluate the effectiveness of the under-mattress monitoring device to aid in the titration process of a mandibular advancement device (MAD) for the management of obstructive sleep apnea (OSA). A secondary aim is to evaluate changes in subjective OSA symptoms and patient's satisfaction with MAD. A third aim is to analyze if there are differences between the sleep parameters recorded by the under-mattress monitor between responders and non-responders to MAD therapy.

Inclusion Criteria:

• Diagnosis of Obstructive Sleep Apnea demonstrated with a sleep study polysomnography or home sleep study (PSG or HSAT), manually scored by a sleep physician according to the 2017 American Academy of Sleep medicine scoring guidelines.
• Willingness to commute to the OFP clinic every 2 weeks during MAD titration period.
• Consent to partake in the study.

Exclusion Criteria:

• Diagnosis of central or mixed sleep apnea.
• Neurocognitive disease.
• Concomitant therapy with PAP therapy.
• Allergic to the appliance material (Polyamide 12).
• Presence of active dental decay, ill-fitting dental restorations, or crown to root ratio unfavorable.
• Inadequate English language comprehension.
• Lack of coordination or dexterity to insert/remove the MAD intraorally.
• Inability to tolerate digital dental impressions.
• Patients with concomitant diagnosed sleep disorders, including narcolepsy, restless leg syndrome, rapid eye movement sleep behavior disorder).