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Dyspnea is common and distressing in patients with acute respiratory failure. In our intensive care unit, some patients receive a cervical erector spinae plane (ESP) block to help relieve dyspnea. This study will observe patients who receive bilateral cervical ESP blocks and measure changes in dyspnea using validated scales at predefined time points over 24 hours. We will also track vital signs, arterial blood gas values, and diaphragm movement on ultrasound.
Prospective, single-cohort observational study in an adult ICU. Consecutive eligible patients with acute respiratory failure who receive bilateral cervical ESP block will be enrolled. Dyspnea severity will be measured using a 100-mm Dyspnea Visual Analog Scale (D-VAS), the Respiratory Distress Observation Scale (RDOS), and the Intensive Care RDOS (IC-RDOS) before the block (baseline) and at 30 minutes, 8 hours, 16 hours, and 24 hours after the block. Vital signs (respiratory rate, heart rate, peripheral oxygen saturation, blood pressure) will be recorded at the same time points. From arterial blood gases, pH, PaO₂, PaCO₂, SaO₂, and HCO₃- will be abstracted. Bilateral diaphragm excursion amplitude will be measured with bedside ultrasound. Statistical plan includes normality checks; repeated-measures ANOVA for parametric data or Friedman test for nonparametric data; paired t-test or Wilcoxon as needed; chi-square or Fisher's exact for categorical variables. Planned sample size: 30 (power analysis for repeated measures with effect size 0.25, α=0.05, power=0.90).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cervical ESP cohort | adults with acute respiratory failure receiving bilateral cervical ESP block |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in Dyspnea by Visual Analog Scale (D-VAS) | Patient-reported dyspnea on a 100-mm line (0=no dyspnea, 100=worst imaginable); measured in mm from 0 anchor to the patient's mark. | Baseline (pre-block), 30 minutes, 8 hours, 16 hours, and 24 hours after the ESP block. |
| Measure | Description | Time Frame |
|---|---|---|
| Respiratory Distress Observation Scale (RDOS) Score | Observer-rated RDOS (higher scores indicate more severe respiratory distress); standard scoring per instrument. | Baseline, 30 minutes, 8 hours, 16 hours, 24 hours post-block. |
| Intensive Care Respiratory Distress Observation Scale (IC-RDOS) Score |
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Inclusion Criteria:
Exclusion Criteria:
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Consecutive adult patients in the mixed medical-surgical ICU of a tertiary university hospital (Hacettepe University Hospital, Ankara, Türkiye). The ICU manages acute respiratory failure due to pneumonia, COPD/asthma, pulmonary edema, and post-operative causes. Patients who receive a cervical ESP block for dyspnea as are observed for changes over 24 hours.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Çağrı Arslan, Resident | Contact | +90 551 722 26 60 | cagriarslan96@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Seda Banu AKINCI, Professor | Hacettepe University | Principal Investigator |
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| ID | Term |
|---|---|
| D004417 | Dyspnea |
| ID | Term |
|---|---|
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
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Observer-rated IC-RDOS (higher scores worse); standard scoring per instrument. |
| Baseline, 30 minutes, 8 hours, 16 hours, 24 hours post-block. |
| Diaphragm Excursion Amplitude on Ultrasound | Peak-to-peak diaphragm excursion amplitude measured bilaterally with bedside ultrasound/M-mode. | Baseline (pre-block), 30 minutes |
| Arterial Blood Gas Parameters: pH, PaO₂, PaCO₂ , SaO₂, HCO₃- | Abstracted from ABGs | Baseline (pre-block), 30 minutes, 8 hours, 16 hours, and 24 hours after the ESP block. |
| Adverse Events Related to ESP Block | Number of participants with any block-related AE within 24 hours, per chart review/clinical documentation. | From block through 24 hours. |
| Respiratory Rate (Breaths/minute) | Respiratory Rate recorded per routine monitoring. | Baseline, 30 minutes, 8 hours, 16 hours, 24 hours post-block. |
| Heart Rate (Beats/minute) | Heart rate recorded per routine monitoring. | Baseline, 30 minutes, 8 hours, 16 hours, 24 hours post-block. |
| SpO₂ (%) | SpO₂ recorded per routine monitoring. | Baseline, 30 minutes, 8 hours, 16 hours, 24 hours post-block. |
| Blood Pressure (mm-Hg) | Blood Pressure recorded per routine monitoring. | Baseline, 30 minutes, 8 hours, 16 hours, 24 hours post-block. |
| D013568 | Pathological Conditions, Signs and Symptoms |