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The aim this prospective observational study is to evaluate the role of Indocyanine Green Fluorescence (ICG) in patients with achalasia underwent to Heller-Dor laparoscopic. The main gol are:
Achalasia is a rare disease of motility characterized by dysfunction of low esophageal sphincter (LES). This disease is divided according to Chicago classification. Laparoscopic Heller - Dor is gold standard of types I and II Achalasia. The use of intraoperative indocyanine green (ICG) fluorescence in recent years is becoming an interesting and innovative tool for surgical procedures. Its use is widely described in surgery The aim of our study is to value the role of ICG for this surgery. The investigators prospectively enrolled achalasic patients undergoing laparoscopic Heller -Dor .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Standard group | IGC group |
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| Measure | Description | Time Frame |
|---|---|---|
| mucosal leak | Directly visualize intraoperatively the presence or absence of an esophageal mucosal lesion through the color change due to indocyanine green fluorescence. | Intraoperative |
| Completeness of myotomy | Intraoperatively visualize the presence or absence of residual muscle fibers after myotomy through the use of indocyanine green fluorescence. | intraoperative |
| Measure | Description | Time Frame |
|---|---|---|
| Length of stay | days of hospitalization from first postoperative day to discarge | From the first to the fourth post-operative day |
| Perioperative complications | Based on Clavien-Dindo classification |
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Inclusion Criteria:
Exclusion Criteria:
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Each patient has type I or type II esophageal achalasia and was treated with the Heller-Dor laparoscopic surgery.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dr. Giuseppe Palomba, MD, Phd fellow | Contact | +393381155483 | giuseppe.palomba@unina.it |
| Name | Affiliation | Role |
|---|---|---|
| Giovanni Aprea, Prof. | Federico II University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Università degli Studi di Napoli, Federico II | Recruiting | Naples | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35472736 | Background | Romanzi A, D'Alba L, Campagna P, Mancini R, Pernazza G. Robotic Heller-Dor procedure for oesophageal achalasia: Fluorescence-guided intraoperative assessment of myotomy. A retrospective single-centre experience. Int J Med Robot. 2022 Aug;18(4):e2411. doi: 10.1002/rcs.2411. Epub 2022 May 4. | |
| 39781145 | Background |
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| ID | Term |
|---|---|
| D004931 | Esophageal Achalasia |
| ID | Term |
|---|---|
| D015154 | Esophageal Motility Disorders |
| D003680 | Deglutition Disorders |
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
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| Perioperative/Periprocedural |
| Patel J, Kalikar V, Patankar R, Supe A. Is Indocyanine Green the New Gold Standard for Checking Completion of Laparoscopic Heller's Cardiomyotomy? Cureus. 2024 Dec 8;16(12):e75344. doi: 10.7759/cureus.75344. eCollection 2024 Dec. |
| 38548426 | Background | Palomba G, Basile R, Capuano M, Pesce M, Rurgo S, Sarnelli G, De Palma GD, Aprea G. Nasogastric tube after laparoscopic Heller-Dor surgery: Do you really need it? Curr Probl Surg. 2024 Apr;61(4):101457. doi: 10.1016/j.cpsurg.2024.101457. Epub 2024 Feb 15. No abstract available. |
| D004066 | Digestive System Diseases |