Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Sarcopenia negatively affects the prognosis of chronic diseases. However, the importance of sarcopenia in patients with idiopathic pulmonary fibrosis (IPF) has been less emphasized. The aim of the study is to determine the prevalence of sarcopenia in patients with IPF and to evaluate the impact of sarcopenia on quality of life and disease progression.
This study was designed as a descriptive cross-sectional. The study included patients diagnosed with IPF. Hand dynamometry and bioelectrical impedance analysis (BIA) were used to for diagnose of sarcopenia. Pulmonary function tests, maximal inspiratory pressure (MIP), and maximal expiratory pressure (MEP) measurements were examined. The 6-minute walk distance (6MWD) and 4-meter walking speed were recorded. The St. George Respiratory Questionnaire (SGRQ) was used to assess quality of life. All patients were evaluated for progressive disease.
The study was designed as a cross-sectional study.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| idiopathic pulmonary fibrosis (IPF) | The prevalence of sarcopenia was investigated in patients with IPF who met the inclusion and exclusion criteria. The relationship between sarcopenia and quality of life and disease progression in patients with IPF was evaluated. |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Hand Grip Strength | Hand Grip Strength (kg)- Grip strength measurement using a hand dynamometer | through study completion, an average of 1 year |
| SMI (skeletal muscle mass index) | SMI (skeletal muscle mass index) (kg/m2) - SMI measurement using the Bioelectrical Impedance Analysis (BIA) device | through study completion, an average of 1 year |
| Forced Expiratory Volume in 1 second (FEV1) | Measurement of FEV1 for the assessment of pulmonary function | through study completion, an average of 1 year |
| Forced Vital Capacity (FVC) | Measurement of FVC for the assessment of pulmonary function | through study completion, an average of 1 year |
| Diffusing Capacity of The Lungs for Carbon Monoxide (DLCO) | Measurement of DLCO for the assessment of pulmonary function. | through study completion, an average of 1 year |
| Total Lung Capacity (TLC) | Measurement of TLC for the assessment of pulmonary function. | through study completion, an average of 1 year |
| Respiratory Muscle Strength | Measurement of maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) for assessment of respiratory muscle strength | through study completion, an average of 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Body Mass Index ( BMI) | kg/m2 | through study completion, an average of 1 year |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Patients included in the study were those diagnosed with IPF according to the ATS/ERS/JRS/ALAT 2022 guidelines and who applied to the Department of Pulmonary Diseases at Mersin University Faculty of Medicine.
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mersin University Faculty of Medicine | Mersin | Mersin | Turkey (Türkiye) |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D054990 | Idiopathic Pulmonary Fibrosis |
| D055948 | Sarcopenia |
| ID | Term |
|---|---|
| D011658 | Pulmonary Fibrosis |
| D017563 | Lung Diseases, Interstitial |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
| Six Minute Walk Test (6MWT) | Distance walked in six minutes (m) | through study completion, an average of 1 year |
| Gait speed | 4-meter walking speed (m/s) | through study completion, an average of 1 year |
| St. George's Respiratory Questionnaire (SGRQ) | The questionnaire is designed to measure quality of life. It consists of symptom, activity, impact, and total scores. Each score ranges from 0 to 100. High scores indicate lower quality of life. | through study completion, an average of 1 year |
| Progressive Disease | Examination of all participants from clinical, physiological, and radiological perspectives | through study completion, an average of 1 year |
| D009133 | Muscular Atrophy |
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D001284 | Atrophy |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |