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Comparison of Transvaginal Natural Orifice Transluminal Endoscopic Surgery and Conventional Laparoscopy in terms of their effects on ovarian reserve in Opportunistic Bilateral Salpingectomy for Permanent Female Sterilization
The study will include participants who apply to our clinic for salpingectomy for contraception and agree to participate in the study. vnotes salpingectomy method or classical laparoscopic salpingectomy will be offered to the patients as two salpingectomy methods and the patient will be included in whichever group in the study. All surgeries will be performed by the same surgeon. 3 months after the date of surgery, the patient will be called for a follow-up for amh repeat and the two groups will be compared both within themselves and with each other to evaluate whether the different surgical technique has an effect on ovarian reserve.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| vnotes salpingectomy performed | Experimental | group of women who underwent salpingectomy with the vnotes method for women who wanted to have their tubes removed for contraception |
|
| laparoscopic salpingectomy performed | Active Comparator | group of women who underwent salpingectomy with the laparoscopic salpingectomy method for women who wanted to have their tubes removed for contraception |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| anti müllerian hormone | Other | participants were checked for amh levels preoperatively |
|
| Measure | Description | Time Frame |
|---|---|---|
| measuring anti-millerian hormone level | To evaluate the effect of two surgical methods on ovarian reserve by measuring serum anti-Müllerian hormone levels (ng/ml) before surgery and after salpingectomy. | amh level (ng/ml) will be checked before the operation, and after 3 months, she will be called for control and measured again. |
| Measure | Description | Time Frame |
|---|---|---|
| comparison of duration of surgery | To compare the success of the two surgical techniques Surgery duration: the time from when the patient first receives anesthesia until they are awakened, recorded in minutes (min) | Perioperative |
| Postoperative hospital stay duration |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gaziosmanpaşa Education and Research Hospital | Istanbul | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34411729 | Result | Yassa M, Kaya C, Kalafat E, Tekin AB, Karakas S, Mutlu MA, Birol P, Tug N. The Comparison of Transvaginal Natural Orifice Transluminal Endoscopic Surgery and Conventional Laparoscopy in Opportunistic Bilateral Salpingectomy for Permanent Female Sterilization. J Minim Invasive Gynecol. 2022 Feb;29(2):257-264.e1. doi: 10.1016/j.jmig.2021.08.009. Epub 2021 Aug 16. | |
| 41662907 |
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The name, surname and personal data of the patients will never be shared with anyone. Data related to the study such as surgical information, amh level, antral follicle count, etc. specified in the informed consent obtained for the study will be used.
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| ID | Term |
|---|---|
| D054304 | Anti-Mullerian Hormone |
| ID | Term |
|---|---|
| D013735 | Testicular Hormones |
| D042341 | Gonadal Hormones |
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |
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| anti müllerian hormon | Diagnostic Test | participants were checked for amh levels at 3 months postoperatively. |
|
The days the patient stays in the hospital, starting from the first day they are admitted for surgery until they are discharged after full recovery following the surgery, will be recorded as days. the number of days the patient stays in the hospital, recorded in days (days) |
| Perioperative |
| postoperative pain | The patient is asked to rate the pain they feel from the moment they wake up after surgery on a scale of 1 to 10. | first hour after surgery |
| Yildiz E, Coskun ES, Timur GY, Bacak HB, Aciyiyen Y, Terkan H, Bilici SR, Ersoy D, Aldanmaz B, Salman S, Celikoglu E. When Performing vNOTES Salpingectomy, Are We Damaging the Ovarian Reserve? Results From a Randomized, Controlled Trial. J Minim Invasive Gynecol. 2026 Feb 7:S1553-4650(26)00103-2. doi: 10.1016/j.jmig.2026.02.009. Online ahead of print. |
| D006023 | Glycoproteins |
| D006001 | Glycoconjugates |
| D002241 | Carbohydrates |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |