Comparison of a 7t MRI to standard of care 1.5t/3t MRI scans to determine if earlier detection of brain metastases are possible on a 7t.

This study is looking at patients diagnosed with small-cell lung cancer & have declined prophylactic cranial irradiation. Patients must have had a 1.5t/3t MRI performed within 4 weeks of consenting to the trial that was negative for brain metastases. Patients will then undergo a 7t MRI & be followed for their standard of care scans for 12 months or until confirmed metastases are detected. Once a patient has confirmed brain mets, their standard of care scans will be used for an analysis compared to the 7t scan to determine if earlier detection of brain micro metastases are feasible.

Inclusion Criteria:

• Patient must have a histologically confirmed diagnosis of small-cell lung cancer (SCLC). • Patient must have an MRI of the brain, performed within 4 weeks prior to consent, documenting no evidence of brain metastases or leptomeningeal disease.
• Patient also must not have a history of brain metastases or leptomeningeal disease.
• Patient must refuse PCI and agree to surveillance with brain MRI scans (1.5T/3T).
• Patient must be ≥ 18 years of age.
• Patient must have ECOG Performance Status of 0-2
• Patients must be able to tolerate the 7T MRI

Exclusion Criteria:

• Patient must not have a contraindication to an MRI, such as implanted metal devices or foreign bodies.
• Patient must not have a contraindication to gadolinium contrast administration during MR imaging.
• Patient must not have other metastatic malignancies requiring current active treatment.
• Pregnant patients are excluded. Pregnancy status will be confirmed verbally.

Patients who present to clinic & who have declined PCI will be presented and offered the study.