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Development and clinical use of pancreatic cancer registry
We plan to collect retrospective and prospective data based on medical data centered on EMR. ∙ This registry is built on EMR data containing specific information on medical provider records and patient health records. It is designed to enable the confirmation of specific treatment history and medical staff records, and to generate highly valid RWD-based evidence through EMR information such as accurate diagnosis of disease, treatment method, symptom changes, monitoring of lab data values, and patient status. ∙ Based on the built registry data, it is possible to conduct research based on evaluation of drug treatment and additional comparison of indications for elderly or poor general condition patients who are excluded from regular clinical trials, as well as research on diagnosis and prognosis. The clinical information and biomarkers of the prospective patient group are analyzed to evaluate the correlation with treatment response, overall and progression-free survival rates.
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| Measure | Description | Time Frame |
|---|---|---|
| Development and clinical use of a pancreatic cancer registry | Development of K-PaC Registry v.2.0: Retrospective data integration from 2010 to 2022 and prospective data collection from more than 811 enrolled patients from 2023 to 2029Creation of clinical evidence (RWE) based on pancreatic cancer real-world data (RWD): 3 or more | From initial diagnosis to death |
| Measure | Description | Time Frame |
|---|---|---|
| Assessing the association between pancreatic cancer biomarker markers and treatment response, overall and progression-free survival | Transcriptome, Whole genome, Epigenome, Proteome, Metabolome | From initial diagnosis to death |
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Inclusion Criteria:
Exclusion Criteria:
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pancreatic cancer
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Cancer Center | Goyang | Gyeonggido | 10408 | South Korea |
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| Label | URL |
|---|---|
| 1\. Guidelines for the Pancreatic Cancer Registry, National Cancer Center Big Data Center | View source |
| 2\. CONNECT Cancer Big Data Library: Pancreatic Cancer Section | View source |
| Korean clinical practice guideline for pancreatic cancer 2021: A summary of evidence-based, multi-disciplinary diagnostic and therapeutic approaches |
| ID | Type | URL | Comment |
|---|---|---|---|
| Study Protocol | View IPD |
There are restrictions under Korea's Personal Information Protection Act.
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| ID | Term |
|---|---|
| D010190 | Pancreatic Neoplasms |
| ID | Term |
|---|---|
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004701 | Endocrine Gland Neoplasms |
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Transcriptome, Whole genome, Epigenome, Proteome, Metabolome
| View source |
1. 1. Guidelines for the Pancreatic Cancer Registry, National Cancer Center Big Data |
| Study Protocol | View IPD | 2. CONNECT Cancer Big Data Library: Pancreatic Cancer Section |
| Study Protocol | View IPD | Korean clinical practice guideline for pancreatic cancer 2021 |
| D004066 |
| Digestive System Diseases |
| D010182 | Pancreatic Diseases |
| D004700 | Endocrine System Diseases |