Predictive Value of CEA and ctDNA in Lung Cancer Recurrence

Predictive Value of CEA and ctDNA for Postoperative Recurrence in Patients With High CEA Sensitivity Lung Cancer

The study aims to investigate the predictive value of CEA levels for postoperative recurrence in the highly sensitive CEA lung cancer patients and to explore whether the dynamic changes of postoperative CEA and MRD in this population are related.This study was carried out to accurately predict the recurrence time, save the time and cost of changing the intervention strategy, and provide more personalized treatment for patients.

This study will collect two groups of cohorts: prospective and retrospective.

Inclusion Criteria:

1. Preoperative CEA > 5mg/l
2. MRD testing was conducted before the operation
3. The primary lesion was resected through surgery
4. There should be at least two CEA and MRD follow-up tests within 2 years after the operation
5. Postoperative pathology confirmed it as a malignant lung tumor

Exclusion Criteria:

1. Those without available imaging records
2. Patients with a history of malignant tumors within the past five years
3. Patients with secondary lung cancer