Trajectories of Anxiety and Depression in Cancer Patients, Risk and Predictive Factors and Supportive Care; Prognostic Awareness and Shared Decision Making.

NEOPSYCO STUDY: Trajectories of Anxiety and Depression in Cancer Patients, Risk and Predictive Factors and Supportive Care; Prognostic Awareness and Shared Decision Making.

To examine the trajectories of anxiety and depression symptoms over the course of oncological disease, and to assess potential predictors-sociodemographic (age, sex, marital status, employment status), clinical (tumor location, stage, treatment type, general health), psychological (coping strategies, quality of life, cognitive difficulties, fear of recurrence), and physical activity-and their association with support needs and utilization of psychosocial services.

The study population consists of consecutive oncology patients recruited across multiple centers, with data collection occurring at baseline (diagnosis or treatment initiation) and at 3-month and 6-month follow-up time points.

Inclusion Criteria:

• Histologically confirmed diagnosis of solid cancer (non-hematologic) at any stage.
• Adult age (>18 years).
• Candidate for perioperative systemic antineoplastic treatment or for advanced disease.
• Willingness to participate in the study and sign the informed consent form, as appropriate, before initiating any study-specific procedures, in accordance with good clinical practice requirements and local regulations.

Exclusion Criteria:

• Presence of a pre-existing psychiatric or neurodegenerative disorder that impairs the patient's ability to participate in the study.
• Presence of reading and writing difficulties that prevent the patient from completing the assessments.
• Receipt of oncological treatment in the past 2 years for another cancer.