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This study aims to develop and validate a contrast-enhanced CT-based deep-learning model for automatic and accurate preoperative discrimination between T1-T2 and T3 renal cell carcinoma. By quantifying the model's diagnostic performance on an independent test set-using AUC, sensitivity, specificity, positive/negative predictive values, and decision-curve analysis-we will establish a decision-support tool that can be seamlessly integrated into clinical PACS, thereby reducing staging errors, refining surgical planning, and improving patient outcomes.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| None intervention | Other | this study is retrospective based on the CT images, which dose include any intervention. |
| Measure | Description | Time Frame |
|---|---|---|
| diagnostic performance | from 2024 to 2027 |
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Inclusion Criteria:
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Patients who underwent surgery at the Department of Urology, Peking University First Hospital, with postoperative pathological confirmation of renal cell carcinoma (RCC), and who also have complete preoperative contrast-enhanced CT datasets (slice thickness ≤1 mm, lossless DICOM) and definitive pathological staging of pT1a-T2b or pT3a.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zejin Ou | Contact | 159 1494 4390 | 2411210230@bjmu.edu.cn |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking University First Hospital, Beijing, | Recruiting | Beijing | China |
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| ID | Term |
|---|---|
| D002292 | Carcinoma, Renal Cell |
| ID | Term |
|---|---|
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
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| D009369 | Neoplasms |
| D007680 | Kidney Neoplasms |
| D014571 | Urologic Neoplasms |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052801 | Male Urogenital Diseases |