Effect of Red and Blue Light Irradiation on Postoperative Wound Healing in Perianal Absces

Effect of Red and Blue Light Irradiation on Postoperative Wound Healing in Perianal Abscess: a Single-center Prospective Open-label Randomized Clinical Trial

This study aims to investigate whether specialized red-blue light irradiation facilitates faster postoperative recovery and reduces complication rates in patients following perianal abscess surgery. A total of 222 eligible patients were randomly allocated equally into three groups (74 per group):①Routine Care Group: Standard wound care including cleansing and dressing changes；②Red Light Therapy Group: Routine care plus red light phototherapy；③Combined Red-Blue Light Therapy Group: Routine care plus concurrent red and blue light phototherapy.Wound healing time and incidence of complications were compared to assess postoperative recovery across interventions. The primary hypothesis posits that adjunctive phototherapy-particularly combined red-blue light irradiation-will significantly enhance wound healing, reduce edema and pain, and decrease complication rates (e.g.bleeding, urinary retention) compared to routine care alone.

Inclusion Criteria:

• Aged between 18 and 75 years;
• Clinical diagnosis of perianal abscess；
• Procedure: Radical resection with incision and drainage.

Exclusion Criteria:

• Concurrent anorectal disorders (hemorrhoids, anal fissure) or malignancies/infectious diseases；
• History of psychiatric disorders；
• Analgesic use within 7 days preoperatively；
• Coagulopathy or cardiac/hepatic dysfunction；
• Pregnancy or lactation；
• Contraindications to phototherapy；
• IBD-related perianal abscess.