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The aim of this observational cohort study was to evaluate adherence to hepatitis B virus (HBV) screening guidelines in a country characterized by low HBV prevalence and assess the potential reactivation and progression of HBV infection in anti-HBV core antigen antibodies (anti-HBc) positive patients receiving corticosteroids for coronavirus disease 2019 (COVID-19).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hepatitis B virus infected patients receiving corticosteroids for COVID-19 pneumonia |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hepatitis B virus infection | Diagnostic Test | anti-hepatitis B virus core antigen positive serologic status |
|
| Measure | Description | Time Frame |
|---|---|---|
| HBV reactivation | number (%) of patients with HBV reactivation | at least 3 months post treatment with corticosteroids |
| number (%) of patients with HBV reactivation | one year |
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Inclusion Criteria:
Exclusion Criteria:
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patients hospitalized and treated with corticosteroids for covid-19
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Medical Centre Ljubljana | Ljubljana | Slovenia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41559625 | Derived | Stupica D, Collinet-Adler S, Grasic JJ, Jurisevic D, Kejzar N, Poljak M, Stamol T. The risk of hepatitis B virus reactivation in COVID-19 patients treated with corticosteroids: a retrospective observational cohort study. BMC Infect Dis. 2026 Jan 20;26(1):352. doi: 10.1186/s12879-026-12610-5. |
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All anonymous data generated or analyzed during this study are available from the corresponding author upon reasonable request.
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| ID | Term |
|---|---|
| D000860 | Hypoxia |
| D006509 | Hepatitis B |
| ID | Term |
|---|---|
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D000086982 | Blood-Borne Infections |
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| D003141 | Communicable Diseases |
| D007239 | Infections |
| D018347 | Hepadnaviridae Infections |
| D004266 | DNA Virus Infections |
| D014777 | Virus Diseases |
| D006525 | Hepatitis, Viral, Human |
| D006505 | Hepatitis |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |