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The purpose of this study is to characterize changes in quality of life in patients who had undergone parathyroidectomy for secondary hyperparathyroidism due to end-stage renal disease, based on data extracted from an established database
Data were retrospectively collected from an established database of patients who underwent surgery for renal secondary hyperparathyroidism (SHPT). Extracted information included demographic and clinical characteristics (age, gender, education level, clinical symptoms), baseline quality of life assessed by the 36-item Short-Form Health Survey (SF-36), and completed follow-up assessments of SF-36 scores, depression, and anxiety at one, three, six months, and one year postoperatively.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Quality of life change in patients Undergoing Parathyroidectomy with end-stage renal failure | Quality of Life Progression in PatientsUndergoing Parathyroidectomy WithSecondary Hyperparathyroidism Due to End-stage Renal Failure |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Quality of life progression after parathyroidectomy | Other | Study the progression of quality of life |
|
| Measure | Description | Time Frame |
|---|---|---|
| Quality of life scores change with respect to time | Quality of life was assessed using the 36-item Short Form Health Survey (SF-36) scale. Completed responses for each of the 36 items were extracted from the database. Item responses were aggregated to calculate scores for each of the eight dimensions. Scores for each dimension range from 0 to 100, with higher scores indicating better health status | up to 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Anxiety and depression score change with respect to time | Anxiety and depression were evaluated using the Hospital Anxiety and Depression Scale (HADS). Completed responses for the 14-item HADS, comprising 7 items each for the anxiety (HADS-A) and depression (HADS-D) subscales, were extracted from the database. Item scores range from 0 to 3, and were summed to yield separate scores for anxiety and depression |
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Inclusion Criteria:
Age ≥18 years； Patients who had undergone parathyroidectomy for secondary hyperparathyroidism due to end-stage renal disease.
Exclusion Criteria:
Patients who underwent kidney transplantation during the study period. Patients with postoperative whole blood parathyroid hormone levels >300 pg/mL within the first week after surgery.
Patients with missing postoperative quality of life assessment data.
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Patients who had undergone parathyroidectomy for secondary hyperparathyroidism due to end-stage renal disease were included in this study
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Chunling Jiang, PhD | Contact | +862885423593 | jiangchunling@scu.edu.cn |
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| up to 1 year |
| Bone pain scores change with respect to time | Bone pain was evaluated using the Numerical Rating Scale (NRS). Completed NRS scores, ranging from 0 to 10, were extracted from the database. In this scale, 0 represents no pain, 1-3 represents mild pain, 4-6 represents moderate pain, 7-9 represents severe pain, and 10 represents the worst pain | up to 1 year |
| Length of hospital stay | an average of 1 week |
| ID | Term |
|---|---|
| D051436 | Renal Insufficiency, Chronic |
| ID | Term |
|---|---|
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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