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Background: Dental implant therapy in the posterior maxilla may be difficult owing to limited bone height after dental extraction with sinus pneumatization. Several approaches for sinus floor elevation have been documented, and hence trans crestal sinus lifting with albumin platelet rich plasma.
Aim of the study: To compare between erythropoietin and albumin platelet rich fibrin transcrestal sinus lifting versus albumin platelet rich fibrin transcrestal sinus lifting using piezoelectric device in patients with atrophic maxilla.
Methods: This study will be carried out as a randomized
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Erythropoietin and albumin PRF gel | Experimental |
| |
| albumin PRF gel | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Erythropoietin and albumin PRF gel + implant placement | Other | This group will be treated by transcrestal sinus lifting with erythropoietin and albumin PRF gel with simultaneous implant placement. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in pain scores | pain will be assessed through a 10 point visual analogue scale (VAS). (0-1=none, 2-4=mild, 5-7=moderate, 8-10=severe). | up to 14 days |
| Change in edema | Edema will be assessed as follows:
| up to 14 days |
| Change in implant stability | implant stability will be assessed using ostell device | immediate and 4 months |
| Measure | Description | Time Frame |
|---|---|---|
| Change in bone gain | amount of sinus bone gain (SBG) which equals implant protrusion length (IPL) added to Peri-implant sinus bone level (PSBL) which is the distance between the apex of the implant and sinus bone level | baseline and 4 months |
| Change in bone density |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hassan M Ruzyqat, BDS | Contact | 01555767730 | hassanmohammadrziqat@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University | Recruiting | Alexandria | Egypt |
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| ID | Term |
|---|---|
| D004921 | Erythropoietin |
| ID | Term |
|---|---|
| D003115 | Colony-Stimulating Factors |
| D006023 | Glycoproteins |
| D006001 | Glycoconjugates |
| D002241 | Carbohydrates |
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| Albumin PRF gel +implant placement | Other | This group (the Control group) will be treated with transcrestal sinus lifting using albumin PRF gel, with simultaneous implant placement. |
|
it will be assessed using CBCT |
| baseline and 4 months |
| D016298 |
| Hematopoietic Cell Growth Factors |
| D016207 | Cytokines |
| D036341 | Intercellular Signaling Peptides and Proteins |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |
| D011506 | Proteins |
| D001685 | Biological Factors |