Inflammatory Biomarkers as Predictors of PONV Following Pediatric Orchiopexy

Association of Preoperative Inflammatory Biomarkers With Postoperative Nausea and Vomiting in Children Undergoing Orchiopexy

Orchiopexy is a common surgical procedure for the treatment of cryptorchidism in the pediatric population, with a high incidence of postoperative nausea and vomiting (PONV).

Recent evidence suggests that systemic inflammation may contribute to PONV pathogenesis, and preoperative inflammatory biomarkers such as NLR, PLR, SII, MLR, and SIRI could serve as predictive indicators.

This prospective observational study aims to evaluate the relationship between these biomarkers and PONV incidence in children undergoing orchiopexy.

Inclusion Criteria:

• Patients aged between 1 and 8 years
• Patients with ASA physical status I-II
• Patients scheduled for elective orchiopexy
• Obtained written informed consent from parents/guardians

Exclusion Criteria:

• Patients younger than 1 year or older than 8 years
• Patients with ASA physical status III or higher
• Presence of acute infection signs
• History of previous nausea or vomiting