Comparison of Postoperative Effects of Articaine and Lidocaine in Mucogingival Surgery

Differences in Soft Tissue Healing and Vascularization Between Articaine and Lidocaine: A Randomized Clinical and Ultrasonographic Study

The aim of this study is to compare and evaluate the effects of using lidocaine 2% (with adrenaline) and articaine 4% (with adrenaline) in free gingival graft (FGG) surgery on postoperative wound healing, changes in blood flow in the surgical area during the healing process, patients' postoperative pain levels, and anxiety levels before and after surgery.

In a prospective randomised controlled trial conducted to investigate the effect of lidocaine and articaine on postoperative free gingival graft healing, wound healing was assessed using EHS, anxiety was assessed using VAS, STAI, and MDAS questionnaires, and ultrasonographic evaluations and PI measurements were used to determine whether there was a difference in wound healing between the two anaesthetics.

Inclusion Criteria:

• Patients> 18 years requiring FGG surgery with ≤ 1 mm width of attached gingiva
• No systemic diseases or pregnancy.
• Smoking ≤10 cigarettes/day
• Full-mouth plaque score and full-mouth bleeding score ≤10% (four sites per tooth).
• Need for FGG due to insufficient attached gingiva
• No history of mucogingival or periodontal surgery at experimental sites

Exclusion Criteria:

• Use of oral contraceptives, psychotropic drugs, sedatives, or NSAIDs
• Allergy or hypersensitivity to local anesthetics,
• Orofacial neurological symptoms,
• Active infection in the surgical area,
• Pathological mental conditions such as dementia or psychosis, or lack of cooperation,