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The reason for this study is to compare the effect of the study drug RAY1225 to semaglutide on blood sugar levels in participants with type 2 diabetes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 6mg RAY1225 | Experimental | 6 milligrams (mg) RAY1225 administered subcutaneously (SC) once every two week. |
|
| 9mg RAY1225 | Experimental | 9 mg RAY1225 administered subcutaneously (SC) once every two week. |
|
| 1 mg Semaglutide | Active Comparator | 1 mg semaglutide administered SC once a week. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| RAY1225 | Drug | Administered SC |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change From Baseline in Hemoglobin A1c (HbA1c) (6 mg and 9 mg) | HbA1c is the glycosylated fraction of hemoglobin A. | Baseline,36 Week |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of Participants Achieving an HbA1c Target Value of <7% | Baseline,36 Week | |
| Percentage of Participants With HbA1c Target Value of <6.5% | Baseline,36 Week | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ji professor | Contact | 88326666 | iao@pkuph.edu.cn |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking University People's Hospital | Beijing | Heibei | China |
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| ID | Term |
|---|---|
| C000591245 | semaglutide |
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| Semaglutide |
| Drug |
Administered SC |
|
| Percentage of Participants With HbA1c Target Value of <5.7% |
| Baseline,36 Week |
| Mean change in fasting serum glucose | Baseline,36 Week |
| Proportion of patients who achieved weight loss of >5%, >10%, and >15% from baseline | Baseline,36 Week |