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The goal for this study is to evaluate the efficacy and safety of RAY1225 versus placebo in participants with type 2 diabetes not under control with diet and exercise alone.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 3mg RAY1225 | Experimental | Participants received 3 milligrams (mg) of RAY1225 as subcutaneous injection once every two week. |
|
| 6mg RAY1225 | Experimental | Participants received 6 milligrams (mg) of RAY1225 as subcutaneous injection once every two week. |
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| 9mg RAY1225 | Experimental | Participants received 9 milligrams (mg) of RAY1225 as subcutaneous injection once every two week. |
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| Placebo | Placebo Comparator | Participants received placebo as subcutaneous injection once every two week. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| RAY1225 | Drug | Administered SC |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change From Baseline in Hemoglobin A1c (HbA1c) | HbA1c is the glycosylated fraction of hemoglobin A. | Baseline,36 Week |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of Participants Achieving an HbA1c Target Value of <7% | Baseline,36 Week | |
| Percentage of Participants With HbA1c Target Value of <6.5% | Baseline,36 Week | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| JI professor | Contact | 88326666 | iao@pkuph.edu.cn |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking University People's Hospital | Beijingcun | Hebei | China |
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| placebo |
| Drug |
Administered SC |
|
| Mean change in fasting serum glucose |
| Baseline,36 Week |
| Proportion of patients who achieved weight loss of >5%, >10%, and >15% from baseline | Baseline,36 Week |