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| ID | Type | Description | Link |
|---|---|---|---|
| NCI-2025-06013 | Other Identifier | NCI-CTRP Clinical Trials Registry |
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To learn about breast cancer survivors' and their family members' knowledge of and interest in learning about environmental exposures related to personal care products. Researchers also want to learn if there is a link between excessive weight and chemicals that may affect hormones.
Primary Objectives:
Excessive body weight and endocrine disrupting chemicals (EDCs) are interconnected risk factors for breast cancer through disruptions in hormone balance, with African American individuals experiencing disproportionate exposure to EDCs through personal care products marketed to people of color. Under-resourced communities face compounding risks including aggressive late-stage diagnoses and healthcare access barriers that contribute to elevated breast cancer mortality. This proposal engages Acres Homes community members, including Active Living After Cancer (ALAC) participants, to assess knowledge and interest in environmental exposure education focused on personal care products, supporting development of the ALAC with Environmental Vitality (ALAC-ENV) intervention and examining associations between EDCs and excessive weight in breast cancer survivors and family members.
Specific Aim 1: Determine survivors' and family members' environmental exposure knowledge. Participants (n=30) will participate in focus group interviews to assess their interest and understanding of environmental exposures with an emphasis on personal care products.
Specific Aim 2: Determine the relationship between exposures to prevalent EDCs and BMI. A cross-sectional design to examine associations between BMI and measurements of non-persistent EDCs in urine and wristband samples of cancer survivors and family members.
Findings will inform an R-level grant to develop a randomized trial testing the efficacy of an adapted ALAC-ENV curriculum for dissemination and implementation in community settings, as well as foundation grant support for a cross-sectional study examining the association between body mass index, EDC exposure, and cancer in Acres Homes within the context of non-medical drivers of health.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pre-Focus Group Survey | Before your focus group session, you will complete computer-based surveys about your age, biological sex, gender, income, highest level of education, marital status, insurance status, and health behaviors. The online surveys may take up to 40 minutes to complete. |
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| Focus Group Session | After completing the pre-focus group surveys, you will be assigned to a focus group. The focus group will include a warm-up discussion (10 minutes), a short audiovisual presentation (5 minutes) describing endocrine-disrupting chemicals (EDCs), and open-ended questions facilitating discussions on environmental exposures and personal care product usage and ALAC program from your perspective (75 minutes). Focus groups will occur by Zoom video conferencing and will be audio- and video-recorded. The recording will be transcribed (written down) word-for-word, but without your name or any other identifying information. The digital audio and video files will be destroyed after they are transcribed. |
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| Post-Focus Group Survey | After your focus group session, you will complete a computer-based survey to help researchers understand the products you use and things that you do in your everyday life, provide urine samples, and wear a wristband. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Surveys | Other | Electronic surveys will completed via REDCap. |
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| Measure | Description | Time Frame |
|---|---|---|
| Outcome Measure | Questionnaires/Videos | Through study completion; an average of 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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MD Anderson Cancer Center
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dede Teteh-Brooks, DRPH | Contact | 713-563-3493 | dkteteh@mdanderson.org |
| Name | Affiliation | Role |
|---|---|---|
| Dede Teteh-Brooks, DRPH | M.D. Anderson Cancer Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The University of Texas M. D. Anderson Cancer Center | Recruiting | Houston | Texas | 77030 | United States |
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| Label | URL |
|---|---|
| MD Anderson Cancer Center Website | View source |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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| ID | Term |
|---|---|
| D011795 | Surveys and Questionnaires |
| D014743 | Videotape Recording |
| ID | Term |
|---|---|
| D003625 | Data Collection |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D017531 | Health Care Evaluation Mechanisms |
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| Video | Other | Focus group sessions and community forums will be conducted via videoconference (Zoom) |
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| D017437 |
| Skin and Connective Tissue Diseases |
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
| D013637 | Tape Recording |
| D001296 | Audiovisual Aids |
| D018961 | Educational Technology |
| D013672 | Technology |
| D013676 | Technology, Industry, and Agriculture |
| D013690 | Television |