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CRF influences engagement in everyday activities, mood, sleep, social relations, school attendance, academic achievement, and quality of life . It was significantly associated with low health-related quality of life in pediatric cancer patients including leukemia . Since attention to managing cRF has been drawn, only a few non-pharmacological strategies were tested for their effectiveness in reducing cRF among children. Physical activity (Pa) has been proven to be the most effective strategy . Yet adherence to Pa remains problematic.
Childhood cancer-related fatigue (CCRF) is a prevalent condition that affects the quality of life in pediatric cancer patients. Gyrokinesis, a holistic exercise method that incorporates principles from yoga, tai chi, and dance, offers potential benefits in managing fatigue through gentle movement and breath work.
According to The American Cancer Society (ACS) provides comprehensive guidelines for cancer training load .The intensity of the exercise refers to the amount of energy expended when performing the activity4. It can be measured subjectively with a self-reported estimate of effort called the rate of perceived exertion on a scale of 1-10. Low-intensity exercise refers to physical activity or effort performed at 1-3 times the intensity of baseline resting energy expenditure (<3 mets-for example, walking). Moderate-intensity exercise refers to physical activity 3-6 times the intensity of baseline, which requires a moderate amount of effort and noticeably accelerates the heart rate (3-6 mets-for example, brisk walking or cycling). Vigorous-intensity exercise refers to physical activity 6 or more times baseline, which requires a large amount of effort and causes rapid breathing and a substantial increase in heart rate (>6 mets-for example, running or jumping rope)
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Gyrokinesis exercise | Experimental | Structure of a Gyrokinesis Session
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| control group | No Intervention | No intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gyrokinesis exercise | Other |
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| Measure | Description | Time Frame |
|---|---|---|
| Pediatric quality of life multidimensional fatigue scale (peds QLMFS): | CRF was measured using the valid and reliable Arabic version of peds QlMFs . It is an 18-item questionnaire including 'general fatigue', 'sleep/rest fatigue', and 'cognitive fatigue'. The three child self-report versions were used depending on the child's age: 5-7 years (young child), 8-12 years (child), and 13-18 years (adolescent). Higher scores indicate less intense fatigue symptoms . Before the cOViD-19 pandemic, a paper-based appropriate version of the scale was completed by children. During the pandemic, the questionnaires were offered to the participants through a link sent to the parent's phones to eliminate cross-infection. | at baseline and at 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| The six-minute walk test (6-MWT) | The 6-MWt is a functional test that measures the functional capacity/endurance and submaximal or maximal effort needed to perform activities of daily living . The primary outcome of this test is the distance covered in meters. a lower score reflects less functional capacity conceptualizing the child's inability to actively participate in functional activities due to cRF .the test is valid and reliable for children with cancer. Two small cones were placed to mark the starting and end points for a 25-meter-long corridor. The heart rate (hR) and oxygen saturation (spO2) were measured 10 min before and one minute after the 6-MWt according to the guidelines of the American thoracic society (ats). |
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Inclusion Criteria:
Diagnosed and treated for a brain tumor during childhood or adolescence (0-≤18 years).
Treated for a PBT during the previous 10 years, starting from date of diagnosis.
Exclusion Criteria:
History of recent poorly controlled seizures.
Motor tics or Tourette syndrome (including family history of tic disorder).
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| faculty of physical therapy ,Cairo University | Cairo | 3753450 | Egypt |
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| ID | Term |
|---|---|
| D005221 | Fatigue |
| ID | Term |
|---|---|
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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RCT
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| at baseline and at 8 weeks |
| Emotional Well-Being | The Children's Depression Inventory (CDI) is scored by summing the responses to its 27 items, with each item having three options scored 0, 1, or 2, resulting in a total score ranging from 0 to 54. Higher scores indicate more severe depressive symptoms. | at baseline and at 8 weeks |
| Blood panel test | Blood samples were collected before and after the experiment to assess changes in serotonin and cortisol levels, as described previously . Venous blood samples (6 mL) were obtained from the antecubital vein using a disposable syringe between 8:00 a.m. and 10:00 a.m. after a fasting period of at least 8 hr. Capillary blood samples were also obtained via the fingertip method, with a minimum volume of 0.3 μL collected for analysis using a portable lactate analyzer. Cortisol can also be measured in the blood, with samples typically taken in the morning when levels peak | at baseline and at 8 weeks |