Cranial Nerve Functions in Behçet's Disease and Their Relationship With Clinical Parameters

Cranial Nerve Functions in Behçet's Disease and Their Relationship With Clinical Parameters

The goal of this study is to find out whether cranial nerves are affected in people with Behçet's Disease (BD), and how this might relate to other disease features. Cranial nerves control important functions such as vision, facial movement, hearing, swallowing, and balance.

The main questions this study will address are:

• Do people with BD have changes in cranial nerve function compared to healthy individuals?
• Are these changes linked to disease duration, symptoms, or lab results?

Participants will:

• Answer questions about their medical history and BD symptoms
• Complete questionnaires on daily function, mood, and autonomic symptoms
• Have a clinical examination of all 12 cranial nerves
• Undergo non-invasive electrical tests to assess nerve function This study will not involve any medications. All procedures will be completed in one visit.

Inclusion Criteria:

• Aged 18-75
• Diagnosed with BD according to ACR/EULAR 2013 criteria (patient group)
• Healthy with no relevant medical history (control group)

Exclusion Criteria:

• Conditions affecting CN assessment (e.g., facial trauma, surgery, radiotherapy)
• Other rheumatologic or autoimmune diseases
• Psychiatric disorders, alcohol/substance abuse
• Pregnant women
• Use of pacemakers or recent botox to masseter muscle