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The goal of this clinical trial is to learn if autism affect motor functions, including muscle strength, balance, and motor control? Additionally, understanding the motor functions, cognitive functions, and brain activation in individuals with autism, and verifying whether motor training can effectively improve muscle strength, balance, and motor control. The main questions aim to answer are:
[primary hypothesis or outcome measure 1]? [primary hypothesis or outcome measure 2]? If there is a comparison group: Researchers will compare [arm information] to see if [insert effects].
Participants will [describe the main tasks participants will be asked to do, interventions they'll be given and use bullets if it is more than 2 items].
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Autism | Experimental |
| |
| Typically developing control | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| VR-based motor training | Behavioral | Six weeks, twice per week. |
|
| Measure | Description | Time Frame |
|---|---|---|
| The performance of movement operational assessment | Participants will take movement operational assessment, which composed of different tests, such as Timed Up and Go Test (TUG), the 10-meter walk test (10MWT) and the 6-minute walk test (6WMT) | 40 minutes |
| The performance of motor coordination control | the performance recorded with Vicon, an motion capture system, and Single Leg Stance Test | 1 hour, twice |
| Measure | Description | Time Frame |
|---|---|---|
| The N-back Task performance | 40 minutes | |
| The performance of Timed Up and Go Test (TUG) | 1 minute, twice | |
| The performance of the 10-meter walk test (10MWT) |
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> The ASD Group
Inclusion criteria:
Exclusion criteria:
a history of major mental illness (e.g., bipolar affective disorder, schizophrenia, or psychosis), neurological diseases (e.g., stroke, lumbar radiculopathy, or spinal cord injury) that hamper walking function, or neurosurgery.
visual impairment and/or hearing impairment that would preclude participation in motor assessment or training.
Inclusion criteria:
Exclusion criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yi Ling Chien, Clinical Professor | Contact | +886 2-23123456 | 266013 | ntuh.peers@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Taiwan University Hospital | Recruiting | Taipei | Taiwan |
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| ID | Term |
|---|---|
| D001321 | Autistic Disorder |
| ID | Term |
|---|---|
| D000067877 | Autism Spectrum Disorder |
| D002659 | Child Development Disorders, Pervasive |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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| 1 minute, twice |
| The performance of 6-minute walk test (6WMT) | 6 minutes, twice |