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Collagenase has gained pace in treating Dupuytrens contracture for some years. Thus this treatment is performed routinely in many orthopaedic and or hand surgical department. One of these benefits of the collagenase treatment is that the patients quickly recover and return to work or daily activities after the treatment. However, one of the often seen complications to the treatment is skin tear. This is reported in 20-80% of cases depending on the degree of contracture. The presence of skin tear leads to prolonged recovery, increased pain, scarring and post pone patients returning to daily activities and work. The investigators hypothesize that prophylactic initiatives with pre-existing products could reduce skin tear after treatment with collagenase injection into the Dupuytren cord.
To the knowledge of the investigators no effective measures exists for preventing skin breakage following collagenase treatment of Dupuytrens disease. In the current study three different skin treatments are tested against a control group to see if skin breakage can be reduced by one of these prophylactic measures.
The study is performed as a prospective randomized non blinded study.
The degree of contraction is measured. Injection of collagenase into the cord. According to randomization the patient will be allocated to one of the following four treatments.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control group | No Intervention | This group will receive standard collagenase injection in the cord | |
| Experimental group | Experimental | This group will receive vaseline treatment, silicone plaster or steristrip on the skin overlying the cord before breakage of the cord |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Silicone plaster or Steristrip or Vaseline | Procedure | Prophylatic treatment of the skin before breakage of the skin in dupuytrens disease |
|
| Measure | Description | Time Frame |
|---|---|---|
| Tear of skin | Does the skin tear when breaking the dupuytren cord? yes or no. There is no recognized scale for this observation. Only the registration of the skin tearing or not. | During breaking af dupuytren cord following collagenase treatment. Time frame is thus within approximately 10 seconds |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zealand University Hospital | Køge | Region Sjælland | 4600 | Denmark |
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| ID | Term |
|---|---|
| D010577 | Petrolatum |
| ID | Term |
|---|---|
| D006838 | Hydrocarbons |
| D009930 | Organic Chemicals |
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