Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This project aims to collaborate with multiple medical institutions to verify the accuracy, stability, and clinical application value of AI algorithms in echocardiographic quantitative measurement through multi-center clinical research. Specific objectives include:
Cardiovascular disease is a major threat to the health of Chinese residents, and echocardiography, as its core diagnostic tool, directly affects clinical decision-making in terms of measurement accuracy and efficiency. However, traditional ultrasound evaluation heavily relies on physician experience, with pain points such as strong subjectivity, time-consuming measurements, and uneven levels of primary diagnosis. There is an urgent need for technological innovation to improve diagnostic standardization. In recent years, artificial intelligence (AI) technology has shown great potential in the field of medical image analysis, which can achieve automated quantitative measurement of cardiac chamber structure and function. However, existing AI models generally have problems such as insufficient multi center validation and limited adaptability to complex cases, which restrict their clinical translation and application.
To overcome these bottlenecks, this project collaborates with multiple medical institutions to conduct clinical research, systematically evaluating the measurement differences between AI algorithms and physicians of different levels, and assessing the accuracy and stability of AI algorithms. The research will focus on verifying the value of AI technology in improving diagnostic consistency, optimizing workflows, and exploring its potential applications in complex cardiovascular diseases. By establishing a standardized evaluation system, this project aims to promote the standardized application of AI ultrasound technology, ultimately achieving the goal of improving diagnosis and treatment efficiency, promoting the sinking of high-quality medical resources, and helping to improve the overall level of cardiovascular disease prevention and treatment.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| AI group | The cardiac chamber size and functional parameters of all 1600 subjects were measured by AI | ||
| Senior physician group | The cardiac chamber size and functional parameters of all 1600 subjects were measured by senior physicians at the PI unit | ||
| Intermediate physician group | The cardiac chamber size and functional parameters of all 1600 subjects were measured by intermediate physicians at each sub center |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| The indicators of left ventricular size and function are measured by AI, senior physicians at the PI unit, and intermediate physicians at each sub center respectively (all parameters are measured by Mindray ultrasonic machines on the machine) | Left ventricular end diastolic volume (EDV, ml), end systolic volume (ESV, ml), and ejection fraction (EF, %) (calculated by (EDV-ESV)/EDV*100% ) in the four chamber view and two chamber view, as well as the Simpson biplane left ventricular volume (ml) and ejection fraction (%) results. | Artificial intelligence and intermediate doctors measurement results of each sub center will be completed within one day after data collection. Senior physicians measurement results of PI unit will be completed within one month after data collection. |
| The indicator of right ventricular function is measured by AI, senior physicians at the PI unit, and intermediate physicians at each sub center respectively (all parameters are measured by Mindray ultrasonic machines on the machine) | Right ventricular area change rate calculated by (EDA-ESA)/EDA*100%. | Artificial intelligence and intermediate doctors measurement results of each sub center will be completed within one day after data collection. Senior physicians measurement results of PI unit will be completed within one month after data collection. |
| The indicators of right ventricular size are measured by AI, senior physicians at the PI unit, and intermediate physicians at each sub center respectively (all parameters are measured by Mindray ultrasonic machines on the machine) | Right ventricular end diastolic area (EDA) and end systolic area (ESA). | Artificial intelligence and intermediate doctors measurement results of each sub center will be completed within one day after data collection. Senior physicians measurement results of PI unit will be completed within one month after data collection. |
| Measure | Description | Time Frame |
|---|---|---|
| Doppler ultrasound measurement indicators by are measured by AI, senior physicians at the PI unit, and intermediate physicians at each sub center respectively (all parameters are measured by Mindray ultrasonic machines on the machine) | Forward blood flow velocity of mitral and tricuspid valve (m/s). | Artificial intelligence and intermediate doctors measurement results of each sub center will be completed within one day after data collection. Senior physicians measurement results of PI unit will be completed within one month after data collection. |
Not provided
Inclusion Criteria:
Age ≥18 - 80 years;
Types of diseases (8 in total, 200 cases each):
Exclusion Criteria:
Not provided
Not provided
Patients who require cardiac ultrasound examination for various reasons in clinical practice. Ultrasound and clinical diagnosis of patients with normal cardiac structure and function, as well as those with coronary heart disease, valve disease, hypertensive heart disease, atrial fibrillation, heart failure, dilated cardiomyopathy, and hypertrophic cardiomyopathy. A total of 1600 adults were enrolled in multiple centers;
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Chunyan Ma the First Hospital of China Medical Univeristy, Ph.D | Contact | 13998816448 | cmu1h_mcy@126.com |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Huainan First People's Hospital | Recruiting | Huainan | Anhui | China |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Mitral valve annulus and tricuspid valve annulus displacement are measured by AI, senior physicians at the PI unit, and intermediate physicians at each sub center respectively (all parameters are measured by Mindray ultrasonic machines on the machine) | Mitral valve annulus and tricuspid valve annulus displacement (mm) | Artificial intelligence and intermediate doctors measurement results of each sub center will be completed within one day after data collection. Senior physicians measurement results of PI unit will be completed within one month after data collection. |
| Union Hospital Affiliated to Fujian Medical University | Recruiting | Fuzhou | Fujian | China |
|
| Meizhou People's Hospital | Recruiting | Meizhou | Guangdong | China |
|
| Shantou Central Hospital | Recruiting | Shantou | Guangdong | China |
|
| Shenzhen Hospital of Fuwai Hospital | Recruiting | Shenzhen | Guangdong | China |
|
| Shenzhen People's Hospital | Recruiting | Shenzhen | Guangdong | China |
|
| Affiliated Hospital of Youjiang Medical University for Nationalities | Recruiting | Baise City | Guangxi | China |
|
| Guilin Hospital of Traditional Chinese Medicine | Recruiting | Guilin | Guangxi | China |
|
| The Fourth Affiliated Hospital of Guangxi Medical University / Liuzhou Workers' Hospital | Recruiting | Liuzhou | Guangxi | China |
|
| Yulin First People's Hospital | Recruiting | Yulin | Guangxi | China |
|
| The Second Affiliated Hospital of Zunyi Medical University | Recruiting | Zunyi | Guizhou | China |
|
| Haikou People's Hospital | Recruiting | Haikou | Hainan | China |
|
| The Second Affiliated Hospital of Hebei Medical University | Recruiting | Shijiazhuang | Hebei | China |
|
| Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Recruiting | Wuhan | Hubei | China |
|
| Loudi First People's Hospital | Recruiting | Loudi | Hunan | China |
|
| Hunan Province Directly Affiliated TCM Hospital | Recruiting | Zhuzhou | Hunan | China |
|
| Baotou No.4 Hospital | Recruiting | Baotou | Inner Mongolia | China |
|
| Shangrao Central Hospital | Recruiting | Shangrao | Jiangxi | China |
|
| Shangrao People's Hospital | Recruiting | Shangrao | Jiangxi | China |
|
| Ansteel Group General Hospital | Recruiting | Anshan | Liaoning | China |
|
| Chaoyang Central Hospital | Recruiting | Chaoyang | Liaoning | China |
|
| Fushun Central Hospital | Recruiting | Fushun | Liaoning | China |
|
| Shengjing Hospital of China Medical University | Recruiting | Shenyang | Liaoning | China |
|
| The First Hospital of China Medical University | Recruiting | Shenyang | Liaoning | China |
|
| Qinghai Provincial Hospital of Cardiovascular and Cerebrovascular Diseases | Recruiting | Xining | Qinghai | China |
|
| The Central Hospital Affiliated to Shandong First Medical University | Recruiting | Tai’an | Shandong | China |
|
| Linfen People's Hospital | Recruiting | Linfen | Shanxi | China |
|
| The Second Affiliated Hospital of Xi'an Jiaotong University | Recruiting | Xi’an | Shanxi | China |
|
| Jiangyou 903 Hospital | Recruiting | Jiangyou | Sichuan | China |
|
| Bishan Hospital Affiliated to Chongqing Medical University | Recruiting | Chongqing | China |
|
| Bishan Hospital Affiliated to Chongqing University of Chinese Medicine (Chongqing Bishan District Hospital of Traditional Chinese Medicine) | Recruiting | Chongqing | China |
|
| Chongqing Hospital of Traditional Chinese Medicine | Recruiting | Chongqing | China |
|
| Chongqing People's Hospital | Recruiting | Chongqing | China |
|
| Fuling Hospital Affiliated to Chongqing University | Recruiting | Chongqing | China |
|
| The First Affiliated Hospital of Army Medical University | Recruiting | Chongqing | China |
|
| The Second Affiliated Hospital of Chongqing Medical University | Recruiting | Chongqing | China |
|
| Shanghai Changzheng Hospital | Recruiting | Shanghai | China |
|
| ID | Term |
|---|---|
| D002318 | Cardiovascular Diseases |
Not provided
Not provided
Not provided