Immune Biomarkers in Prostate Cancer Patients Treated With Brachytherapy

Immune Biomarkers in Prostate Cancer Patients Treated With Brachytherapy (ImmunBioProBrachy)

Analysis of peripheral immune cells before, during, and after brachytherapy treatment. Corresponding analysis of tissue samples collected during brachytherapy treatment.

Inclusion Criteria Arm 1:

• Primary treatment with I-125 seeds or HDR-BT
• No previous treatment for prostate cancer
• Age ≥ 18 years

Inclusion Criteria Arm 2:

• HDR- or PDR-BT
• No radiation therapy within three months before salvage treatment
• Complete documentation available on previous treatment for prostate cancer
• No history of prostatectomy
• Age ≥ 18 years

Exclusion Criteria:

• Pre-existent auto-immune disease
• patients under bloodthinning medication
• substance abuse